Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | MTNR1A | P48039 | 5/20 | 0.34 |
| ▸ | MTNR1B | P49286 | 4/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | FASN | P49327 | 1/20 | 0.32 |
| ▸ | NAMPT | P43490 | 1/20 | 0.31 |
| ▸ | DHODH | Q02127 | 2/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17337254 | 0.89 | MTNR1A (0.35) | KDM4EALDH1A1GAAMTNR1AMTNR1B | |
| SCHEMBL17337256 | 0.89 | MTNR1A (0.35) | KDM4EALDH1A1GAAMTNR1AMTNR1B | |
| SCHEMBL17347384 | 0.83 | NAMPT (0.36) | MTNR1AMTNR1BNAMPTL3MBTL1 | |
| SCHEMBL23129670 | 0.83 | NAMPT (0.36) | MTNR1AMTNR1BNAMPTL3MBTL1 | |
| SCHEMBL23130137 | 0.79 | NPC1 (0.35) | MTNR1AMTNR1BNPC1RAB9ADHODH | |
| SCHEMBL17347387 | 0.79 | NPC1 (0.35) | MTNR1AMTNR1BNPC1RAB9ADHODH | |
| SCHEMBL17336991 | 0.79 | PARP1 (0.34) | NPC1RAB9ADHODHL3MBTL1SMYD3 | |
| SCHEMBL17336990 | 0.79 | PARP1 (0.34) | NPC1RAB9ADHODHL3MBTL1SMYD3 | |
| SCHEMBL18966854 | 0.78 | MTNR1A (0.38) | MTNR1AMTNR1BNAMPT | |
| SCHEMBL17337131 | 0.77 | PARP1 (0.33) | ALDH1A1MTNR1AMTNR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3882252-A1 | BETA-LACTAMASE INHIBITORS | Venatorx Pharmaceuticals, Inc. (US) | 2021-09-22 | — | — | EP | disclosed |