Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 4/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | APOB | P04114 | 2/20 | 0.31 |
| ▸ | MTTP | P55157 | 2/20 | 0.31 |
| ▸ | CA12 | O43570 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | CA7 | P43166 | 1/20 | 0.31 |
| ▸ | CA9 | Q16790 | 1/20 | 0.31 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17337294 | 0.91 | CA12 (0.33) | MAPTKDM4EMEN1ALDH1A1KMT2A | |
| SCHEMBL23129924 | 0.91 | CA12 (0.33) | MAPTKDM4EMEN1ALDH1A1KMT2A | |
| SCHEMBL17337133 | 0.85 | RAB9A (0.35) | PARP1MEN1ALDH1A1KMT2AAPOB | |
| SCHEMBL17337541 | 0.85 | RAB9A (0.35) | PARP1MEN1ALDH1A1KMT2AAPOB | |
| SCHEMBL23129662 | 0.84 | KMT2A (0.32) | KDM4EALDH1A1KMT2A | |
| SCHEMBL17347818 | 0.84 | KMT2A (0.32) | KDM4EALDH1A1KMT2A | |
| SCHEMBL17337192 | 0.81 | TSHR (0.37) | MAPTKDM4EMEN1ALDH1A1KMT2A | |
| SCHEMBL17337334 | 0.81 | TSHR (0.37) | MAPTKDM4EMEN1ALDH1A1KMT2A | |
| SCHEMBL23129992 | 0.81 | TSHR (0.38) | MAPTKDM4EALDH1A1 | |
| SCHEMBL17337419 | 0.81 | TSHR (0.38) | MAPTKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3882252-A1 | BETA-LACTAMASE INHIBITORS | Venatorx Pharmaceuticals, Inc. (US) | 2021-09-22 | — | — | EP | disclosed |