Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 3/20 | 0.36 |
| ▸ | CA1 | P00915 | 3/20 | 0.36 |
| ▸ | CA2 | P00918 | 3/20 | 0.36 |
| ▸ | CA7 | P43166 | 3/20 | 0.36 |
| ▸ | CA9 | Q16790 | 3/20 | 0.36 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.36 |
| ▸ | MTNR1A | P48039 | 3/20 | 0.35 |
| ▸ | MTNR1B | P49286 | 3/20 | 0.35 |
| ▸ | OPRD1 | P41143 | 4/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.33 |
| ▸ | OPRK1 | P41145 | 3/20 | 0.33 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17347663 | 0.89 | CA12 (0.38) | CA12CA1CA2CA7CA9 | |
| SCHEMBL23129930 | 0.89 | CA12 (0.38) | CA12CA1CA2CA7CA9 | |
| SCHEMBL17347836 | 0.86 | CA12 (0.39) | CA12CA1CA2CA7CA9 | |
| SCHEMBL23130037 | 0.86 | CA12 (0.39) | CA12CA1CA2CA7CA9 | |
| SCHEMBL19663658 | 0.83 | CA12 (0.38) | CA12CA1CA2CA7CA9 | |
| SCHEMBL23837309 | 0.82 | MTNR1A (0.34) | CA12CA1CA2CA7CA9 | |
| SCHEMBL17347750 | 0.81 | MTNR1A (0.33) | CA12CA1CA2CA7CA9 | |
| SCHEMBL23129972 | 0.81 | MTNR1A (0.33) | CA12CA1CA2CA7CA9 | |
| SCHEMBL17347824 | 0.80 | CA12 (0.36) | CA12CA1CA2CA7CA9 | |
| SCHEMBL23129679 | 0.80 | OPRD1 (0.35) | OPRD1OPRM1OPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3882252-A1 | BETA-LACTAMASE INHIBITORS | Venatorx Pharmaceuticals, Inc. (US) | 2021-09-22 | — | — | EP | disclosed |