Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 2/20 | 0.39 |
| ▸ | CA2 | P00918 | 2/20 | 0.39 |
| ▸ | SUCNR1 | Q9BXA5 | 7/20 | 0.39 |
| ▸ | HDAC4 | P56524 | 3/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.38 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.38 |
| ▸ | PSMB9 | P28065 | 1/20 | 0.38 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.38 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29101054 | 0.93 | TDP1 (0.43) | CA1CA2SUCNR1HDAC4HDAC1 | |
| SCHEMBL29101055 | 0.93 | TDP1 (0.43) | CA1CA2SUCNR1HDAC4HDAC1 | |
| SCHEMBL23827436 | 0.90 | SUCNR1 (0.43) | CA1CA2SUCNR1HDAC4HDAC1 | |
| SCHEMBL23827435 | 0.90 | SUCNR1 (0.43) | CA1CA2SUCNR1HDAC4HDAC1 | |
| SCHEMBL29101097 | 0.90 | SUCNR1 (0.43) | CA1CA2SUCNR1HDAC4HDAC1 | |
| SCHEMBL23827389 | 0.78 | PSMB8 (0.41) | CA1CA2SUCNR1HDAC4HDAC1 | |
| SCHEMBL23827392 | 0.78 | PSMB8 (0.41) | CA1CA2SUCNR1HDAC4HDAC1 | |
| SCHEMBL22012931 | 0.77 | CA1 (0.48) | CA1CA2HDAC4HDAC1TDP1 | |
| SCHEMBL22012933 | 0.77 | CA1 (0.48) | CA1CA2HDAC4HDAC1TDP1 | |
| SCHEMBL23838044 | 0.76 | HDAC4 (0.38) | CA1CA2SUCNR1HDAC4HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3882246-A1 | MONOBACTAM COMPOUNDS AND USE THEREFOR | Nanjing Sanhome Pharmaceutical Co., Ltd. (CN) | 2021-09-22 | — | — | EP | disclosed |