Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 3/20 | 0.44 |
| ▸ | CA2 | P00918 | 3/20 | 0.44 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.42 |
| ▸ | HDAC4 | P56524 | 3/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.42 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.42 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.42 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.42 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.42 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.41 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.41 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.41 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22013869 | 1.00 | CA1 (0.44) | CA1CA2SIRT5HDAC4HDAC1 | |
| SCHEMBL22012933 | 0.82 | CA1 (0.48) | CA1CA2SIRT5HDAC4HDAC1 | |
| SCHEMBL22012931 | 0.82 | CA1 (0.48) | CA1CA2SIRT5HDAC4HDAC1 | |
| SCHEMBL29967445 | 0.79 | DGAT1 (0.50) | CA1CA2AAK1USP30PRMT5 | |
| SCHEMBL19195067 | 0.79 | DGAT1 (0.50) | CA1CA2AAK1USP30PRMT5 | |
| SCHEMBL860377 | 0.79 | DGAT1 (0.53) | CA1CA2HDAC1AAK1USP30 | |
| SCHEMBL24811141 | 0.77 | USP30 (0.56) | CA1CA2AAK1USP30PRMT5 | |
| SCHEMBL16947773 | 0.75 | DGAT1 (0.50) | CA1CA2AAK1USP30PRMT5 | |
| SCHEMBL29050482 | 0.75 | USP30 (0.47) | AAK1USP30PRMT5WDR77DGAT1 | |
| SCHEMBL30231262 | 0.75 | USP30 (0.47) | AAK1USP30PRMT5WDR77DGAT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3882246-A1 | MONOBACTAM COMPOUNDS AND USE THEREFOR | Nanjing Sanhome Pharmaceutical Co., Ltd. (CN) | 2021-09-22 | — | — | EP | disclosed |