Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.44 |
| ▸ | RAB9A | P51151 | 4/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | TLR8 | Q9NR97 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | APP | P05067 | 1/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | PPARD | Q03181 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28683905 | 0.83 | MAPT (0.48) | MAPTRAB9ANPSR1TLR8KMT2A | |
| SCHEMBL29379396 | 0.83 | MAPT (0.48) | MAPTRAB9ANPSR1TLR8KMT2A | |
| SCHEMBL24086141 | 0.76 | NPSR1 (0.42) | MAPTRAB9ANPSR1TLR8KMT2A | |
| SCHEMBL13903788 | 0.74 | APP (0.64) | MAPTRAB9ANPSR1KMT2AKDM4E | |
| SCHEMBL13903800 | 0.74 | APP (0.64) | MAPTRAB9ANPSR1KMT2AKDM4E | |
| SCHEMBL13903795 | 0.74 | APP (0.64) | MAPTRAB9ANPSR1KMT2AKDM4E | |
| SCHEMBL7813641 | 0.73 | RAB9A (0.60) | MAPTRAB9AKMT2AKDM4EALDH1A1 | |
| SCHEMBL21664333 | 0.72 | NPC1 (0.50) | MAPTRAB9ANPSR1KMT2AKDM4E | |
| SCHEMBL23965747 | 0.72 | PPARD (0.47) | MAPTRAB9AKMT2AKDM4EALDH1A1 | |
| SCHEMBL14101346 | 0.72 | HTT (0.38) | MAPTRAB9ANPSR1KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3604301-B1 | 4-PYRIDONE COMPOUND OR SALT THEREOF, AND PHARMACEUTICAL COMPOSITION AND FORMULATION INCLUDING SAME | FUJIFILM CORP (JP) | 2021-09-22 | — | — | EP | disclosed |