Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 4/20 | 0.60 |
| ▸ | NPC1 | O15118 | 3/20 | 0.60 |
| ▸ | APEX1 | P27695 | 2/20 | 0.60 |
| ▸ | MITF | O75030 | 1/20 | 0.60 |
| ▸ | POLB | P06746 | 1/20 | 0.60 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.60 |
| ▸ | PPARD | Q03181 | 1/20 | 0.58 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 5/20 | 0.52 |
| ▸ | TMPRSS15 | P98073 | 2/20 | 0.52 |
| ▸ | TP53 | P04637 | 4/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.50 |
| ▸ | ACP1 | P24666 | 1/20 | 0.50 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | STAT1 | P42224 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24331728 | 0.76 | HDAC6 (0.68) | RAB9ANPC1APEX1MITFPOLB | |
| SCHEMBL27839973 | 0.75 | DYRK1A (0.63) | RAB9ANPC1APEX1MITFPOLB | |
| SCHEMBL14077515 | 0.73 | MAPT (0.54) | RAB9ANPC1POLBDYRK1AMAPT | |
| SCHEMBL23839400 | 0.73 | MAPT (0.44) | RAB9ANPC1POLBPPARDMAPT | |
| SCHEMBL14189673 | 0.73 | RAB9A (0.70) | RAB9ANPC1APEX1MITFPOLB | |
| SCHEMBL16847224 | 0.73 | HTT (0.67) | RAB9ANPC1POLBDYRK1AMAPT | |
| SCHEMBL15993576 | 0.72 | MAPT (0.50) | RAB9ANPC1POLBDYRK1AMAPT | |
| SCHEMBL23965747 | 0.72 | PPARD (0.47) | RAB9ANPC1PPARDMAPTTMPRSS15 | |
| SCHEMBL2793209 | 0.71 | DYRK1A (0.65) | RAB9ANPC1APEX1MITFPOLB | |
| SCHEMBL25408657 | 0.71 | TMPRSS15 (0.68) | RAB9ANPC1TMPRSS15SMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1091958-A1 | SALTS OF PAROXETINE | SMITHKLINE BEECHAM PLC (GB) | 2001-04-18 | — | — | EP | disclosed |
| WO-2000001692-A1 | SALTS OF PAROXETINE | SMITHKLINE BEECHAM PLC (GB) | 2000-01-13 | — | — | WO | disclosed |