Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 5/20 | 0.48 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.48 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.48 |
| ▸ | FAAH | O00519 | 3/20 | 0.48 |
| ▸ | PTPN7 | P35236 | 4/20 | 0.39 |
| ▸ | HMGCR | P04035 | 2/20 | 0.39 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.35 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL379177 | 0.84 | MGLL (0.39) | MGLLPTGS1PTGS2FAAH | |
| SCHEMBL6078313 | 0.78 | PTPN7 (0.39) | MGLLPTGS1PTGS2FAAHPTPN7 | |
| SCHEMBL5069988 | 0.74 | NR1H2 (0.44) | KCNH2 | |
| SCHEMBL11484029 | 0.68 | PTPN7 (0.46) | PTPN7HMGCRKCNH2RECQLTDP1 | |
| SCHEMBL17965749 | 0.68 | PTPN7 (0.46) | PTPN7HMGCRKCNH2RECQLTDP1 | |
| SCHEMBL17965756 | 0.68 | — | — | |
| SCHEMBL9367475 | 0.68 | PTPN7 (0.46) | PTPN7HMGCRKCNH2RECQLTDP1 | |
| SCHEMBL21294357 | 0.68 | PTPN7 (0.46) | PTPN7HMGCRKCNH2RECQLTDP1 | |
| SCHEMBL17377642 | 0.68 | PTPN7 (0.46) | PTPN7HMGCRKCNH2RECQLTDP1 | |
| SCHEMBL29020570 | 0.68 | PTPN7 (0.46) | PTPN7HMGCRKCNH2RECQLTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220202837-A1 | COMPOSITIONS AND METHODS FOR MODIFICATION OF BIOMOLECULES | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2022-06-30 | — | — | US | disclosed |
| US-20200046742-A1 | COMPOSITIONS AND METHODS FOR MODIFICATION OF BIOMOLECULES | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2020-02-13 | — | — | US | disclosed |
| US-10434111-B2 | Compositions and methods for modification of biomolecules | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2019-10-08 | — | — | US | disclosed |
| US-20160243135-A1 | Compositions and Methods for Modification of Biomolecules | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2016-08-25 | — | — | US | disclosed |
| US-9260371-B2 | Compositions and methods for modification of biomolecules | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2016-02-16 | — | — | US | disclosed |
| EP-1812031-B1 | COMPOSITIONS AND METHODS FOR MODIFICATION OF BIOMOLECULES | UNIV CALIFORNIA (US) | 2015-06-24 | — | — | EP | disclosed |
| US-20130344527-A1 | Compositions and Methods for Modification of Biomolecules | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2013-12-26 | — | — | US | disclosed |
| US-8461298-B2 | Compositions and methods for modification of biomolecules | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2013-06-11 | — | — | US | disclosed |
| US-8431558-B2 | Compositions and methods for modification of biomolecules | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2013-04-30 | — | — | US | disclosed |
| US-20110213123-A1 | COMPOSITIONS AND METHODS FOR MODIFICATION OF BIOMOLECULES | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2011-09-01 | — | — | US | disclosed |
| US-7807619-B2 | cycloalkyne compounds reacting with an azide moiety on a target biomolecule, by biochemical conjugation; for its application in vivo (on the cell surface or intracellularly) or in vitro (synthesis of peptides); labeling | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2010-10-05 | — | — | US | disclosed |
| US-20090068738-A1 | COMPOSITIONS AND METHODS FOR MODIFICATION OF BIOMOLECULES | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2009-03-12 | — | — | US | disclosed |
| EP-1812031-A2 | COMPOSITIONS AND METHODS FOR MODIFICATION OF BIOMOLECULES | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2007-08-01 | — | — | EP | disclosed |
| US-20060110782-A1 | cycloalkyne compounds reacting with an azide moiety on a target biomolecule, by biochemical conjugation; for its application in vivo (on the cell surface or intracellularly) or in vitro (synthesis of peptides); labeling | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2006-05-25 | — | — | US | disclosed |
| WO-2006050262-A2 | COMPOSITIONS AND METHODS FOR MODIFICATION OF BIOMOLECULES | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2006-05-11 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220202837-A1 | COMPOSITIONS AND METHODS FOR MODIFICATION OF BIOMOLECULES | PTMS, QPCT, ANPEP | MGLL 2030/4885PTGS1 2564/4885PTGS2 2726/4885 |
| US-20130344527-A1 | Compositions and Methods for Modification of Biomolecules | PTMS, QPCT, ANPEP | MGLL 2030/4885PTGS1 2564/4885PTGS2 2726/4885 |
| US-10434111-B2 | Compositions and methods for modification of biomolecules | PTMS, QPCT, ANPEP | MGLL 2030/4885PTGS1 2564/4885PTGS2 2726/4885 |
| US-20090068738-A1 | COMPOSITIONS AND METHODS FOR MODIFICATION OF BIOMOLECULES | PTMS, QPCT, ANPEP | MGLL 2030/4885PTGS1 2564/4885PTGS2 2726/4885 |
| US-20160243135-A1 | Compositions and Methods for Modification of Biomolecules | PTMS, QPCT, ANPEP | MGLL 2030/4885PTGS1 2564/4885PTGS2 2726/4885 |
| US-20110213123-A1 | COMPOSITIONS AND METHODS FOR MODIFICATION OF BIOMOLECULES | PTMS, QPCT, ANPEP | MGLL 2030/4885PTGS1 2564/4885PTGS2 2726/4885 |
| US-20200046742-A1 | COMPOSITIONS AND METHODS FOR MODIFICATION OF BIOMOLECULES | PTMS, QPCT, ANPEP | MGLL 2030/4885PTGS1 2564/4885PTGS2 2726/4885 |
| US-20060110782-A1 | cycloalkyne compounds reacting with an azide moiety on a target biomolecule, by biochemical conjugation; for its application in vivo (on the cell surface or intracellularly) or in vitro (synthesis of peptides); labeling | PTMS, QPCT, DNPEP | MGLL 2317/4885PTGS1 2434/4885PTGS2 2792/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.