Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 12/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | BLM | P54132 | 2/20 | 0.39 |
| ▸ | GMNN | O75496 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | THPO | P40225 | 1/20 | 0.39 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | FAAH | O00519 | 4/20 | 0.36 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.36 |
| ▸ | GSK3A | P49840 | 2/20 | 0.33 |
| ▸ | GSK3B | P49841 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | WRN | Q14191 | 1/20 | 0.31 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2383963 | 0.84 | MGLL (0.48) | MGLLFAAHPTGS1PTGS2 | |
| SCHEMBL10606609 | 0.77 | — | — | |
| SCHEMBL900640 | 0.72 | DRD3 (0.46) | ALDH1A1MAPT | |
| SCHEMBL718144 | 0.69 | MGLL (0.41) | MGLLALDH1A1BLMGMNNLMNA | |
| SCHEMBL4004252 | 0.66 | MGLL (0.36) | MGLLALDH1A1BLMGMNNLMNA | |
| SCHEMBL3152143 | 0.61 | — | — | |
| SCHEMBL27317183 | 0.61 | USP2 (0.30) | — | |
| SCHEMBL5167647 | 0.59 | — | — | |
| SCHEMBL55369 | 0.59 | — | — | |
| SCHEMBL8471148 | 0.59 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150133653-A1 | COMPOUNDS AND BIOLOGICAL MATERIALS AND USES THEREOF | PHOTOBIOTICS LIMITED (GB) | 2015-05-14 | — | — | US | disclosed |
| US-20120070377-A1 | COMPOUNDS AND BIOLOGICAL MATERIALS AND USES THEREOF | PHOTOBIOTICS LIMITED (GB) | 2012-03-22 | — | — | US | disclosed |
| EP-2408779-A1 | COMPOUNDS AND BIOLOGICAL MATERIALS AND USES THEREOF | Photobiotics Limited (GB) | 2012-01-25 | — | — | EP | disclosed |
| WO-2010106341-A1 | COMPOUNDS AND BIOLOGICAL MATERIALS AND USES THEREOF | PHOTOBIOTICS LIMITED (GB) | 2010-09-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150133653-A1 | COMPOUNDS AND BIOLOGICAL MATERIALS AND USES THEREOF | SSB, HLA-B, BDKRB1 | MGLL 4110/4885ALDH1A1 371/4885BLM 38/4885 |
| US-20120070377-A1 | COMPOUNDS AND BIOLOGICAL MATERIALS AND USES THEREOF | SSB, HLA-B, BDKRB1 | MGLL 3830/4885ALDH1A1 278/4885BLM 37/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.