Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 5/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.38 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | CASP1 | P29466 | 1/20 | 0.35 |
| ▸ | CASP7 | P55210 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18908668 | 0.85 | SMN1; SMN2 (0.59) | SMN1; SMN2TP53HPGDALDH1A1KMT2A | |
| SCHEMBL23840993 | 0.81 | SMN1; SMN2 (0.45) | SMN1; SMN2TP53HPGDALDH1A1KMT2A | |
| SCHEMBL22247051 | 0.81 | ALDH1A1 (0.55) | HPGDALDH1A1POLBHTT | |
| SCHEMBL23841000 | 0.81 | SMN1; SMN2 (0.45) | SMN1; SMN2TP53HPGDALDH1A1KMT2A | |
| SCHEMBL22484141 | 0.80 | SMN1; SMN2 (0.47) | SMN1; SMN2TP53HPGDALDH1A1KMT2A | |
| SCHEMBL19776847 | 0.80 | SMN1; SMN2 (0.47) | SMN1; SMN2TP53HPGDALDH1A1KMT2A | |
| SCHEMBL16316312 | 0.80 | POLB (0.50) | SMN1; SMN2TP53HPGDALDH1A1KMT2A | |
| SCHEMBL20144535 | 0.79 | SMN1; SMN2 (0.41) | SMN1; SMN2TP53HPGDALDH1A1KMT2A | |
| SCHEMBL10224055 | 0.78 | SMN1; SMN2 (0.49) | SMN1; SMN2TP53HPGDALDH1A1KMT2A | |
| SCHEMBL20349713 | 0.77 | ALDH1A1 (0.46) | SMN1; SMN2TP53HPGDALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11319540-B2 | HIF 1-alpha antisense oligonucleotides | OLIPASS CORPORATION (KR) | 2022-05-03 | — | — | US | disclosed |
| US-20210292767-A1 | HIF 1-ALPHA ANTISENSE OLIGONUCLEOTIDES | OLIPASS CORPORATION (KR) | 2021-09-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11319540-B2 | HIF 1-alpha antisense oligonucleotides | HIF1A, HIF1AN, UPF1 | SMN1; SMN2 423/4885TP53 652/4885HPGD 1869/4885 |
| US-20210292767-A1 | HIF 1-ALPHA ANTISENSE OLIGONUCLEOTIDES | HIF1A, HIF1AN, UPF1 | SMN1; SMN2 423/4885TP53 652/4885HPGD 1869/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.