Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY4R | P50391 | 15/20 | 0.37 |
| ▸ | NPY1R | P25929 | 9/20 | 0.37 |
| ▸ | NPY5R | Q15761 | 8/20 | 0.37 |
| ▸ | NPY2R | P49146 | 5/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.30 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24917381 | 0.97 | ALOX15 (0.36) | NPY4RNPY1RNPY5RNPY2RALOX15 | |
| SCHEMBL22871751 | 0.89 | NPY4R (0.34) | NPY4RNPY1RNPY5RNPY2RALOX15 | |
| SCHEMBL27113590 | 0.86 | NPY4R (0.41) | NPY4RNPY1RNPY5RNPY2RALOX15 | |
| SCHEMBL20221707 | 0.85 | MEN1 (0.40) | NPY4RNPY1RNPY5RNPY2RALOX15 | |
| SCHEMBL23690778 | 0.85 | MEN1 (0.40) | NPY4RNPY1RNPY5RNPY2RALOX15 | |
| SCHEMBL14845337 | 0.85 | NPY4R (0.38) | NPY4RNPY1RNPY5RNPY2RALOX15 | |
| SCHEMBL4572264 | 0.84 | NPY4R (0.36) | NPY4RNPY1RNPY5RNPY2RALOX15 | |
| SCHEMBL26880961 | 0.84 | NPY4R (0.36) | NPY4RNPY1RNPY5RNPY2RALOX15 | |
| SCHEMBL15478607 | 0.83 | NPY4R (0.36) | NPY4RNPY1RNPY5RNPY2RALOX15 | |
| SCHEMBL13769032 | 0.83 | NPY4R (0.36) | NPY4RNPY1RNPY5RNPY2RALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210292767-A1 | HIF 1-ALPHA ANTISENSE OLIGONUCLEOTIDES | OLIPASS CORPORATION (KR) | 2021-09-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210292767-A1 | HIF 1-ALPHA ANTISENSE OLIGONUCLEOTIDES | HIF1A, HIF1AN, UPF1 | NPY4R 4195/4885NPY1R 3533/4885NPY5R 4587/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.