SCHEMBL238415

SCHEMBL238415

CC(C)(C)OC(=O)NCCCC(=O)O

nearest known ligand 0.64

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.64
GAA P10253 1/20 0.64
KMT2A Q03164 1/20 0.64
TDP1 Q9NUW8 1/20 0.62
MAOA P21397 1/20 0.54
MAOB P27338 1/20 0.54
CA1 P00915 8/20 0.51
CA2 P00918 8/20 0.51
CA12 O43570 4/20 0.51
CA9 Q16790 4/20 0.51
HTT P42858 2/20 0.46
ADRA1A P35348 1/20 0.46
SIGMAR1 Q99720 1/20 0.45
EPHX1 P07099 1/20 0.44
PRMT1 Q99873 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28063880 0.98 MEN1 (0.62) MEN1GAAKMT2ATDP1MAOA
SCHEMBL904074 0.94 TDP1 (0.66) MEN1GAAKMT2ATDP1MAOA
SCHEMBL12680329 0.93 MEN1 (0.57) MEN1GAAKMT2ATDP1MAOA
SCHEMBL7911543 0.93 TDP1 (0.69) MEN1GAAKMT2ATDP1MAOA
SCHEMBL22276615 0.93 TDP1 (0.69) MEN1GAAKMT2ATDP1MAOA
SCHEMBL2702010 0.93 TDP1 (0.69) MEN1GAAKMT2ATDP1MAOA
SCHEMBL826376 0.93 TDP1 (0.69) MEN1GAAKMT2ATDP1MAOA
SCHEMBL22276602 0.93 TDP1 (0.69) MEN1GAAKMT2ATDP1MAOA
SCHEMBL16487196 0.93 TDP1 (0.69) MEN1GAAKMT2ATDP1MAOA
SCHEMBL826329 0.93 TDP1 (0.69) MEN1GAAKMT2ATDP1MAOA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 2399 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122010913-A Rhodamine-marked isoquinoline derivative and preparation method and application thereof 淮阴师范学院 2026-05-12 CN claimed
CN-119143776-B Small-molecule fluorescent probe compound and preparation method and application thereof 中国药科大学 2025-02-28 CN claimed
CN-119143776-A Small-molecule fluorescent probe compound and preparation method and application thereof 中国药科大学 2024-12-17 CN claimed
CN-118894858-A BRD4/PLK1 double-target small molecule fluorescent probe and preparation method and application thereof 山东第一医科大学(山东省医学科学院) 2024-11-05 CN claimed
CN-118662656-A Releasable S02Macromolecular vesicles of (2), and preparation method and application thereof 上海大学 2024-09-20 CN claimed
CN-118546199-A Preparation method of prostate cancer targeted fluorescent contrast agent, reagent and application of contrast agent and reagent 新斗生物科技(苏州)有限公司 2024-08-27 CN claimed
CN-117534721-A Preparation method of hederagenin derivative 烟台大学 2024-02-09 CN claimed
CN-117362387-A Benzenesulfonamide piperazinone glycine derivative as well as preparation method and application thereof 山东大学 2024-01-09 CN claimed
CN-113512035-B Dihydropyrimidine-pomalidomide conjugate, and preparation method and application thereof 山东大学 2023-11-24 CN claimed
CN-117025699-A Synthesis method of larotinib key intermediate 泰州学院 2023-11-10 CN claimed
CN-105814031-A Sulfonates of furan-2,5-dimethanol and (tetrahydrofuran-2,5-diyl)dimethanol and derivatives thereof 阿彻丹尼尔斯米德兰德公司 2016-07-27 CN claimed
WO-2016029146-A1 SPECIFIC INHIBITORS OF METHIONYL-TRNA SYNTHETASE UNIVERSITY OF WASHINGTON (US) 2016-02-25 WO claimed
CN-104497095-A Epandrosterone and dehydroepiandrosterone derivatives, preparation method thereof, and applications of derivatives in preparation of drugs used for preventing breast cancer UNIV EAST CHINA NORMAL 2015-04-08 CN claimed
US-20140309192-A1 MODULATORS OF THE G PROTEIN-COUPLED MAS RECEPTOR AND THE TREATMENT OF DISORDERS RELATED THERETO ARENA PHARMACEUTICALS, INC, 2014-10-16 US claimed
US-20100311694-A1 Set of Geldanamycin Derivatives and Their Preparation Methods INSTITUTE OF MEDICINAL BIOTECHNOLOGY, CHINESE ACADEMY OF MEDICAL SCIENCES (CN) 2010-12-09 US claimed
EP-2253621-A1 A SET OF GELDANAMYCIN DERIVATIVES AND THEIR PREPARATION METHODS Institute Of Medicinal Biotechnology, Chinese Academy of Medical Sciences (CN) 2010-11-24 EP claimed
EP-0934065-B1 NOVEL CRYPTOPHYCIN DERIVATIVES AS ANTI-NEOPLASTIC AGENTS UNIV HAWAII (US) 2006-06-07 EP claimed
US-6680311-B1 ANTICARCINOGENIC, ANTITUMOR AND ANTIPROLIFERATIVE AGENTS ELI LILLY AND COMPANY 2004-01-20 US claimed
US-6004823-A Compounds SMITHKLINE BEECHAM CORPORATION (US) 1999-12-21 US claimed
CN-1233957-A Pharmaceutical compositions LILLY CO ELI (US) 1999-11-03 CN claimed