SCHEMBL826329

SCHEMBL826329

CC(C)(C)OC(=O)NCCCCCCC(=O)O

nearest known ligand 0.69

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 1/20 0.69
MEN1 O00255 1/20 0.60
GAA P10253 1/20 0.60
KMT2A Q03164 1/20 0.60
MAOA P21397 1/20 0.59
MAOB P27338 1/20 0.59
ADRA1A P35348 1/20 0.56
CA12 O43570 5/20 0.55
CA1 P00915 5/20 0.55
CA2 P00918 5/20 0.55
CA9 Q16790 5/20 0.55
PRMT1 Q99873 1/20 0.55
CYP3A4 P08684 1/20 0.49
EPHX2 P34913 2/20 0.48
PLA2G2A P14555 1/20 0.47
CHRM2 P08172 2/20 0.47
CHRM4 P08173 2/20 0.47
CHRM5 P08912 2/20 0.47
CHRM1 P11229 2/20 0.47
CHRM3 P20309 2/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1931146 1.00 TDP1 (0.69) TDP1MEN1GAAKMT2AMAOA
SCHEMBL826755 1.00 TDP1 (0.69) TDP1MEN1GAAKMT2AMAOA
SCHEMBL7911543 1.00 TDP1 (0.69) TDP1MEN1GAAKMT2AMAOA
SCHEMBL826376 1.00 TDP1 (0.69) TDP1MEN1GAAKMT2AMAOA
SCHEMBL2702010 1.00 TDP1 (0.69) TDP1MEN1GAAKMT2AMAOA
SCHEMBL16487196 1.00 TDP1 (0.69) TDP1MEN1GAAKMT2AMAOA
SCHEMBL345583 1.00 TDP1 (0.69) TDP1MEN1GAAKMT2AMAOA
SCHEMBL22276615 1.00 TDP1 (0.69) TDP1MEN1GAAKMT2AMAOA
SCHEMBL22276602 1.00 TDP1 (0.69) TDP1MEN1GAAKMT2AMAOA
SCHEMBL8002115 1.00 TDP1 (0.69) TDP1MEN1GAAKMT2AMAOA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 284 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119185569-A Sustained release delivery system comprising a traceless linker 诺华股份有限公司 2024-12-27 CN claimed
CN-118078995-B Dual-targeting high-water-solubility micromolecular boron drug as well as preparation method and application thereof 东莞市人民医院 2024-08-23 CN claimed
CN-118078995-A Dual-targeting high-water-solubility micromolecular boron drug as well as preparation method and application thereof 东莞市人民医院 2024-05-28 CN claimed
CN-114682309-B Chip, method for producing a chip and use of a chip 深圳华大生命科学研究院 2024-04-09 CN claimed
CN-117362387-A Benzenesulfonamide piperazinone glycine derivative as well as preparation method and application thereof 山东大学 2024-01-09 CN claimed
CN-116411354-A Gene chip with modified surface of solid phase carrier 深圳华大生命科学研究院 2023-07-11 CN claimed
CN-114682309-A Chip, method for preparing chip and use of chip 深圳华大生命科学研究院 2022-07-01 CN claimed
CN-112770782-A Sustained delivery of angiopoietin-like 3 polypeptides 诺华股份有限公司 2021-05-07 CN claimed
CN-110603060-A Sustained release delivery system comprising traceless linker 诺华股份有限公司 2019-12-20 CN claimed
US-20260092057-A1 BCL-XL/BCL-2 DEGRADERS AND USES THEREOF KYMERA THERAPEUTICS INC (US) 2026-04-02 US disclosed
EP-4676929-A1 PROTAC DEGRADERS OF MLLT1 AND/OR MLLT3 Dark Blue Therapeutics Ltd (GB) 2026-01-14 EP disclosed
WO-2025262297-A1 PROTAC DEGRADERS OF MLLT1 AND/OR MLLT3 DARK BLUE THERAPEUTICS LTD (GB) 2025-12-26 WO disclosed
EP-4667467-A1 PROTAC DEGRADERS OF MLLT1 AND/OR MLLT3 Dark Blue Therapeutics Ltd (GB) 2025-12-24 EP disclosed
US-20250382292-A1 COMPOUNDS FOR TREATING LIGHT CHAIN AMYLOIDOSIS PROTEGO BIOPHARMA INC (US) 2025-12-18 US disclosed
EP-0494248-A1 ANTI-THROMBOTIC PEPTIDES AND PSEUDOPEPTIDES RHONE-POULENC RORER INTERNATIONAL (HOLDINGS) INC. (US) 1992-07-15 EP disclosed
US-5039805-A Novel benzoic and phenylacetic acid derivatives HOFFMANN-LA ROCHE INC. (US) 1991-08-13 US disclosed
WO-1991004746-A1 ANTI-THROMBOTIC PEPTIDES AND PSEUDOPEPTIDES RHONE-POULENC RORER INTERNATIONAL (HOLDINGS) INC. (US) 1991-04-18 WO disclosed
EP-0372486-A2 Benzoic-acid phenylacetic-acid derivatives, their preparation and their use as medicines F. HOFFMANN-LA ROCHE AG (CH) 1990-06-13 EP disclosed
US-4161521-A Somatostatin analogs MERCK & CO., INC. (US) 1979-07-17 US disclosed
US-4133805-A INHIBIT RELEASE OR PITUITARY GROWTH HORMONE, GLUCAGON, AND INSULIN AMERICAN HOME PRODUCTS CORPORATION (US) 1979-01-09 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260092057-A1 BCL-XL/BCL-2 DEGRADERS AND USES THEREOF BCL2L2, BCL2A1, BCL2L1 TDP1 3952/4885MEN1 3960/4885GAA 3879/4885
US-20250382292-A1 COMPOUNDS FOR TREATING LIGHT CHAIN AMYLOIDOSIS TTR, CRYAA, BCL6 TDP1 1226/4885MEN1 2701/4885GAA 26/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.