Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.69 |
| ▸ | MEN1 | O00255 | 1/20 | 0.60 |
| ▸ | GAA | P10253 | 1/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.60 |
| ▸ | MAOA | P21397 | 1/20 | 0.59 |
| ▸ | MAOB | P27338 | 1/20 | 0.59 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.56 |
| ▸ | CA12 | O43570 | 5/20 | 0.55 |
| ▸ | CA1 | P00915 | 5/20 | 0.55 |
| ▸ | CA2 | P00918 | 5/20 | 0.55 |
| ▸ | CA9 | Q16790 | 5/20 | 0.55 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.48 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.47 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.47 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.47 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.47 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.47 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1931146 | 1.00 | TDP1 (0.69) | TDP1MEN1GAAKMT2AMAOA | |
| SCHEMBL826755 | 1.00 | TDP1 (0.69) | TDP1MEN1GAAKMT2AMAOA | |
| SCHEMBL7911543 | 1.00 | TDP1 (0.69) | TDP1MEN1GAAKMT2AMAOA | |
| SCHEMBL826376 | 1.00 | TDP1 (0.69) | TDP1MEN1GAAKMT2AMAOA | |
| SCHEMBL826329 | 1.00 | TDP1 (0.69) | TDP1MEN1GAAKMT2AMAOA | |
| SCHEMBL16487196 | 1.00 | TDP1 (0.69) | TDP1MEN1GAAKMT2AMAOA | |
| SCHEMBL345583 | 1.00 | TDP1 (0.69) | TDP1MEN1GAAKMT2AMAOA | |
| SCHEMBL22276615 | 1.00 | TDP1 (0.69) | TDP1MEN1GAAKMT2AMAOA | |
| SCHEMBL22276602 | 1.00 | TDP1 (0.69) | TDP1MEN1GAAKMT2AMAOA | |
| SCHEMBL8002115 | 1.00 | TDP1 (0.69) | TDP1MEN1GAAKMT2AMAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 61 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4734988-A1 | HETEROBIFUNCTIONAL COMPOUNDS AND METHODS OF USE THEREOF | The Board of Trustees of the Leland Stanford Junior University (US) | 2026-05-06 | — | — | EP | disclosed |
| EP-4709720-A1 | INHIBITORS AND DEGRADERS OF PIP4K PROTEIN | Larkspur Biosciences, Inc. (US) | 2026-03-18 | — | — | EP | disclosed |
| US-20250382292-A1 | COMPOUNDS FOR TREATING LIGHT CHAIN AMYLOIDOSIS | PROTEGO BIOPHARMA INC (US) | 2025-12-18 | — | — | US | disclosed |
| US-20250345446-A1 | BIFUNCTIONAL MOLECULES THAT SELECTIVELY INDUCE DEGRADATION OF EXTRACELLULAR TARGETS IN LYSOSOMES | DRAUPNIR BIO APS (DK) | 2025-11-13 | — | — | US | disclosed |
| EP-4618755-A1 | INHIBITORS AND DEGRADERS OF PIP4K PROTEIN | Larkspur Biosciences, Inc. (US) | 2025-09-24 | — | — | EP | disclosed |
| EP-4543858-A1 | BIFUNCTIONAL MOLECULES THAT SELECTIVELY INDUCE DEGRADATION OF EXTRACELLULAR TARGETS IN LYSOSOMES | Draupnir Bio ApS (DK) | 2025-04-30 | — | — | EP | disclosed |
| US-20250090658-A1 | POLYMER ADJUVANT | OXFORD UNIVERSITY INNOVATION LIMITED (GB) | 2025-03-20 | — | — | US | disclosed |
| WO-2025007026-A1 | HETEROBIFUNCTIONAL COMPOUNDS AND METHODS OF USE THEREOF | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) | 2025-01-02 | — | — | WO | disclosed |
| CN-119161340-A | PROTAC molecule derived based on AZD5305, and preparation method and application thereof | 中国药科大学 | 2024-12-20 | — | — | CN | disclosed |
| CN-115666575-B | Compounds and uses thereof | 福宏治疗公司 | 2024-12-10 | — | — | CN | disclosed |
| US-9242951-B2 | Covalent inhibition of bacterial quorum sensing | The National Institute for Biotechnology in the Negev Ltd. (IL) | 2016-01-26 | — | — | US | disclosed |
| WO-2015195563-A1 | ANTIBACTERIAL AGENTS | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2015-12-23 | — | — | WO | disclosed |
| CN-102482244-B | covalent inhibition of bacterial quorum sensing | NATIONAL INSTITUTE FOR BIOTECHNOLOGY IN THE NEGEV (IL) | 2015-09-09 | — | — | CN | disclosed |
| US-20140073690-A1 | COVALENT INHIBITION OF BACTERIAL QUORUM SENSING | NAT INST FOR BIOTECHNOLOGY IN THE NEGEV LTD (IL) | 2014-03-13 | — | — | US | disclosed |
| US-8501969-B2 | Covalent inhibition of bacterial quorum sensing | The National Institute for Biotechnology in the Negev Ltd. (IL) | 2013-08-06 | — | — | US | disclosed |
| US-20120135925-A1 | Covalent Inhibition of Bacterial Quorum Sensing | The National Institute for Biotechnology in the Negev Ltd. (IL) | 2012-05-31 | — | — | US | disclosed |
| CN-102482244-A | Covalent inhibition of bacterial quorum sensing | NAT INST FOR BIOTECHNOLOGY IN THE NEGEV | 2012-05-30 | — | — | CN | disclosed |
| EP-2448930-A1 | COVALENT INHIBITION OF BACTERIAL QUORUM SENSING | The National Institute for Biotechnology in the Negev Ltd. (IL) | 2012-05-09 | — | — | EP | disclosed |
| EP-1091958-A1 | SALTS OF PAROXETINE | SMITHKLINE BEECHAM PLC (GB) | 2001-04-18 | — | — | EP | disclosed |
| WO-2000001692-A1 | SALTS OF PAROXETINE | SMITHKLINE BEECHAM PLC (GB) | 2000-01-13 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250345446-A1 | BIFUNCTIONAL MOLECULES THAT SELECTIVELY INDUCE DEGRADATION OF EXTRACELLULAR TARGETS IN LYSOSOMES | SORT1, SCARB1, LAMP1 | TDP1 2734/4885MEN1 2813/4885GAA 42/4885 |
| US-20250090658-A1 | POLYMER ADJUVANT | TLR3, TLR9, TLR1 | TDP1 2113/4885MEN1 3645/4885GAA 2228/4885 |
| US-20140073690-A1 | COVALENT INHIBITION OF BACTERIAL QUORUM SENSING | BLVRB, DBI, COASY | TDP1 2006/4885MEN1 4573/4885GAA 3452/4885 |
| US-20120135925-A1 | Covalent Inhibition of Bacterial Quorum Sensing | BLVRB, DBI, COASY | TDP1 2006/4885MEN1 4573/4885GAA 3452/4885 |
| US-20250382292-A1 | COMPOUNDS FOR TREATING LIGHT CHAIN AMYLOIDOSIS | TTR, CRYAA, BCL6 | TDP1 1226/4885MEN1 2701/4885GAA 26/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.