Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 3/20 | 0.51 |
| ▸ | NOS2 | P35228 | 3/20 | 0.48 |
| ▸ | NOS3 | P29474 | 2/20 | 0.48 |
| ▸ | NOS1 | P29475 | 1/20 | 0.48 |
| ▸ | GRM5 | P41594 | 1/20 | 0.45 |
| ▸ | TKT | P29401 | 2/20 | 0.42 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.41 |
| ▸ | KDM1A | O60341 | 1/20 | 0.40 |
| ▸ | MAOA | P21397 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | SLC19A2 | O60779 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | CASP1 | P29466 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | VCP | P55072 | 1/20 | 0.38 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.38 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.38 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8049756 | 0.88 | BACE1 (0.49) | BACE1NOS2NOS3NOS1TKT | |
| SCHEMBL750976 | 0.86 | TLR8 (0.49) | BACE1NOS2NOS3NOS1TLR8 | |
| SCHEMBL28020387 | 0.85 | TLR8 (0.47) | BACE1NOS2NOS3NOS1TLR8 | |
| SCHEMBL27725467 | 0.85 | TLR8 (0.47) | BACE1NOS2NOS3NOS1TLR8 | |
| SCHEMBL11401202 | 0.85 | TLR8 (0.47) | BACE1NOS2NOS3NOS1TLR8 | |
| SCHEMBL6982374 | 0.85 | TLR8 (0.47) | BACE1NOS2NOS3NOS1TLR8 | |
| Hydrochloric Acid SCHEMBL8582822 | 0.83 | TLR8 (0.46) | BACE1NOS2NOS3NOS1TLR8 | |
| SCHEMBL293456 | 0.83 | — | — | |
| SCHEMBL30154778 | 0.83 | — | — | |
| SCHEMBL13699313 | 0.82 | BACE1 (0.44) | BACE1NOS2NOS3NOS1GRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 38 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111643129-B | Chitosan and polyethylene glycol copolymer and method and apparatus for sealing vascular perforations using the same | 通合公司 | 2024-06-11 | — | — | CN | disclosed |
| CN-110952077-B | Method for forming metal film | 株式会社FLOSFIA | 2022-09-13 | — | — | CN | disclosed |
| CN-113336750-B | Dithioacetal-containing pyridopyrimidone derivative and preparation and application thereof | 贵州大学 | 2022-06-07 | — | — | CN | disclosed |
| EP-2990503-B1 | METHOD OF FORMING METAL FILM | FLOSFIA INC (JP) | 2022-01-12 | — | — | EP | disclosed |
| CN-113336750-A | Dithioacetal-containing pyridopyrimidone derivative and preparation and application thereof | 贵州大学 | 2021-09-03 | — | — | CN | disclosed |
| US-20210221784-A1 | COMPOUNDS AND COMPOSITIONS FOR THE TREATMENT OF PAIN | UNIVERSITÉ DE STRASBOURG (FR) | 2021-07-22 | — | — | US | disclosed |
| EP-3749305-A1 | COMPOUNDS AND COMPOSITIONS FOR THE TREATMENT OF PAIN | Université de Strasbourg (FR) | 2020-12-16 | — | — | EP | disclosed |
| CN-111643129-A | Chitosan and polyethylene glycol copolymers and methods and devices for sealing vascular perforations using the same | 通合公司 | 2020-09-11 | — | — | CN | disclosed |
| CN-110952077-A | Method for forming metal film | 株式会社FLOSFIA | 2020-04-03 | — | — | CN | disclosed |
| CN-105386008-B | Method for forming metal film | 株式会社FLOSFIA | 2020-01-21 | — | — | CN | disclosed |
| US-6468741-B1 | Electrochemiluminescent rhenium moieties | IGEN INTERNATIONAL, INC. | 2002-10-22 | — | — | US | disclosed |
| US-5811236-A | QUANTITATIVE, QUALITATIVE ANALYSIS | IGEN INTERNATIONAL, INC. (US) | 1998-09-22 | — | — | US | disclosed |
| US-5716781-A | FORMING A SOLUTION CONTAINING AN ANALYTE COMPRISING FIRST CHEMILUMINESCENT COMPLEX AND AN INTERNAL STANDARD CONTAINING OSMIUM BIPYRIDYL COMPLEX, INDEPENDENTLY MEASURING ELECTROLUMINESCENCE EMITTED BY ANALYTE AND STANDARD | IGEN INTERNATIONAL INC. (US) | 1998-02-10 | — | — | US | disclosed |
| US-5591581-A | Electrochemiluminescent rhenium moieties and methods for their use | IGEN, INC. (US) | 1997-01-07 | — | — | US | disclosed |
| EP-0339086-B1 | ELECTROCHEMILUMINESCENT RHENIUM MOIETIES AND METHODS | IGEN INC (US) | 1996-09-11 | — | — | EP | disclosed |
| EP-0674176-A1 | Electrochemiluminescent rhenium moieties and methods of production | IGEN, INC. (US) | 1995-09-27 | — | — | EP | disclosed |
| EP-0339086-A4 | ELECTROCHEMILUMINESCENT RHENIUM MOIETIES AND METHODS. | IGEN INC (US) | 1990-02-20 | — | — | EP | disclosed |
| EP-0339086-A1 | ELECTROCHEMILUMINESCENT RHENIUM MOIETIES AND METHODS | IGEN, INC. (US) | 1989-11-02 | — | — | EP | disclosed |
| WO-1989004302-A1 | ELECTROCHEMILUMINESCENT RHENIUM MOIETIES AND METHODS | IGEN, INC. (US) | 1989-05-18 | — | — | WO | disclosed |
| US-4457932-A | GASTROINTESTINAL DISORDERS | BRISTOL-MYERS COMPANY (US) | 1984-07-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210221784-A1 | COMPOUNDS AND COMPOSITIONS FOR THE TREATMENT OF PAIN | ACHE, TRPV1, OPRL1 | BACE1 3964/4885NOS2 1125/4885NOS3 725/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.