Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR8 | Q9NR97 | 11/20 | 0.49 |
| ▸ | BACE1 | P56817 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.44 |
| ▸ | NOS2 | P35228 | 2/20 | 0.44 |
| ▸ | NOS3 | P29474 | 1/20 | 0.44 |
| ▸ | NOS1 | P29475 | 1/20 | 0.44 |
| ▸ | TLR7 | Q9NYK1 | 2/20 | 0.43 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28020387 | 0.98 | TLR8 (0.47) | TLR8BACE1TDP1L3MBTL1LIPG | |
| SCHEMBL11401202 | 0.98 | TLR8 (0.47) | TLR8BACE1TDP1L3MBTL1LIPG | |
| SCHEMBL6982374 | 0.98 | TLR8 (0.47) | TLR8BACE1TDP1L3MBTL1LIPG | |
| SCHEMBL27725467 | 0.98 | TLR8 (0.47) | TLR8BACE1TDP1L3MBTL1LIPG | |
| Hydrochloric Acid SCHEMBL8582822 | 0.96 | TLR8 (0.46) | TLR8BACE1TDP1L3MBTL1LIPG | |
| SCHEMBL8049756 | 0.94 | BACE1 (0.49) | TLR8BACE1TDP1L3MBTL1LIPG | |
| SCHEMBL28906708 | 0.89 | TLR8 (0.42) | TLR8BACE1LIPGNOS1TLR7 | |
| SCHEMBL2384178 | 0.86 | BACE1 (0.51) | TLR8BACE1TDP1NOS2NOS3 | |
| SCHEMBL28155486 | 0.84 | BACE1 (0.40) | TLR8BACE1TDP1L3MBTL1LIPG | |
| SCHEMBL28963267 | 0.83 | TLR8 (0.37) | TLR8BACE1TDP1L3MBTL1LIPG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 71 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105085506-B | The medical usage of 2 [epoxide of 4 (benzoxazoles 2) phenoxy group] fatty acyl pyridine amine | 湖南大学 | 2018-01-19 | — | — | CN | claimed |
| CN-105085480-B | 2‑[4‑（The epoxide of quinoxaline 2）Phenoxy group] fatty acyl pyridine amine medical usage | 湖南大学 | 2017-12-29 | — | — | CN | claimed |
| CN-105085386-B | The medical usage of 2 (4 phenoxy-phenoxy) fatty acyl pyridine amine | 湖南大学 | 2017-10-31 | — | — | CN | claimed |
| CN-105085385-B | The medical usage of 2 [4 (epoxide of pyridine 2) phenoxy group] fatty acyl pyridine amine | 湖南大学 | 2017-10-31 | — | — | CN | claimed |
| CN-105085480-A | Medical application of 2-[4-(quinoxaline-2-oxyl)phenoxyl]fatty acyl pyridylamine | UNIV HUNAN | 2015-11-25 | — | — | CN | claimed |
| CN-105085506-A | Medical application of 2-[4-(benzoxazole-2-oxyl)phenoxyl]fatty acyl pyridylamine | UNIV HUNAN | 2015-11-25 | — | — | CN | claimed |
| CN-105085385-A | Medical application of 2-[4-(pyridine-2-oxyl)phenoxyl]fatty acyl pyridylamine | UNIV HUNAN | 2015-11-25 | — | — | CN | claimed |
| CN-105085386-A | Medical application of 2-(4-phenoxyphenoxy)fatty acyl pyridylamine | UNIV HUNAN | 2015-11-25 | — | — | CN | claimed |
| CN-102421807-A | Catalyst, method for preparing polyolefin composition and polyolefin composition | DOW GLOBAL TECHNOLOGIES INC | 2012-04-18 | — | — | CN | claimed |
| US-4914077-A | GOOD HUE AND STABILITY | EASTMAN KODAK COMPANY (US) | 1990-04-03 | — | — | US | claimed |
| CN-111263766-B | Iridium complex compound, composition containing the compound and solvent, organic electroluminescent element containing the compound, display device and lighting device | 三菱化学株式会社 | 2024-04-02 | — | — | CN | disclosed |
| CN-116655702-A | Iridium complex compound and composition containing the same and solvent | 三菱化学株式会社 | 2023-08-29 | — | — | CN | disclosed |
| CN-113966553-A | Composition for organic electroluminescent element, display device, and lighting device | 三菱化学株式会社 | 2022-01-21 | — | — | CN | disclosed |
| CN-113874467-A | Composition for organic electroluminescent element, method for producing organic electroluminescent element, and display device | 三菱化学株式会社 | 2021-12-31 | — | — | CN | disclosed |
| CN-113272313-A | Iridium complex compound | 三菱化学株式会社 | 2021-08-17 | — | — | CN | disclosed |
| CN-100396677-C | 2-thio-substituted imidazole derivatives and their use in pharmaceutics | MERCKLE GMBH (DE) | 2008-06-25 | — | — | CN | disclosed |
| WO-2007083239-A1 | PYRIDINE DERIVATIVES AS SODIUM CHANNEL MODULATORS | PFIZER LIMITED (GB) | 2007-07-26 | — | — | WO | disclosed |
| US-20060235054-A1 | 2-Thio-substituted imidazole derivatives and their use in pharmaceutics | MERCKLE-GMBH (DE) | 2006-10-19 | — | — | US | disclosed |
| CN-1675197-A | 2-thio-substituted imidazole derivatives and their use in pharmaceutics | MERCKLE GMBH (DE) | 2005-09-28 | — | — | CN | disclosed |
| US-4596872-A | Imidazo[1,2-a]pyridines, and process for their preparation | SCHERING A.G. (DE) | 1986-06-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060235054-A1 | 2-Thio-substituted imidazole derivatives and their use in pharmaceutics | IL2, TPMT, IFNG | TLR8 160/4885BACE1 3377/4885TDP1 1108/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.