Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IKBKB | O14920 | 4/20 | 0.63 |
| ▸ | RAF1 | P04049 | 1/20 | 0.43 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | AKT1 | P31749 | 1/20 | 0.43 |
| ▸ | AKT2 | P31751 | 1/20 | 0.43 |
| ▸ | KDR | P35968 | 1/20 | 0.43 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.43 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.43 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.43 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.43 |
| ▸ | DYRK2 | Q92630 | 1/20 | 0.43 |
| ▸ | NEK1 | Q96PY6 | 1/20 | 0.43 |
| ▸ | PRKAB1 | Q9Y478 | 1/20 | 0.43 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.38 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.35 |
| ▸ | ALPL | P05186 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL23830489 | 0.98 | IKBKB (0.61) | IKBKBRAF1RPS6KB1MAPK1AKT1 | |
| SCHEMBL23842730 | 0.77 | IKBKB (0.65) | IKBKBRAF1RPS6KB1MAPK1AKT1 | |
| SCHEMBL24357633 | 0.75 | IKBKB (0.38) | IKBKBRAF1RPS6KB1MAPK1AKT1 | |
| Hydrochloric Acid SCHEMBL23830744 | 0.75 | IKBKB (0.62) | IKBKBRAF1RPS6KB1MAPK1AKT1 | |
| SCHEMBL23842726 | 0.69 | IKBKB (0.67) | IKBKBMAPK1NFE2L2FGFR1 | |
| SCHEMBL13504045 | 0.69 | IKBKB (0.41) | IKBKBNFE2L2POLBKCNH2 | |
| Hydrochloric Acid SCHEMBL23830478 | 0.68 | IKBKB (0.65) | IKBKBMAPK1NFE2L2FGFR1 | |
| SCHEMBL23842727 | 0.67 | IKBKB (0.62) | IKBKB | |
| SCHEMBL23830806 | 0.65 | HPGD (0.44) | IKBKB | |
| Hydrochloric Acid SCHEMBL23830762 | 0.65 | IKBKB (0.60) | IKBKB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210292305-A1 | Cyclic Ureas | SIRONAX LTD (KY) | 2021-09-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210292305-A1 | Cyclic Ureas | RIPK1, RIPK3, RIPK4 | IKBKB 288/4885RAF1 66/4885RPS6KB1 441/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.