Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | S1PR1 | P21453 | 3/20 | 0.43 |
| ▸ | S1PR3 | Q99500 | 3/20 | 0.43 |
| ▸ | S1PR5 | Q9H228 | 3/20 | 0.43 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.41 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.41 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | DPP4 | P27487 | 3/20 | 0.40 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31530916 | 1.00 | ALDH1A1 (0.47) | ALDH1A1S1PR1S1PR3S1PR5S1PR4 | |
| SCHEMBL31530882 | 0.93 | ALDH1A1 (0.42) | ALDH1A1S1PR1S1PR3S1PR5S1PR4 | |
| SCHEMBL14509674 | 0.85 | GNAI3 (0.49) | ALDH1A1S1PR1S1PR3S1PR5S1PR4 | |
| SCHEMBL14539275 | 0.83 | S1PR1 (0.56) | ALDH1A1S1PR1S1PR3S1PR5S1PR4 | |
| SCHEMBL22363324 | 0.83 | S1PR1 (0.56) | ALDH1A1S1PR1S1PR3S1PR5S1PR4 | |
| SCHEMBL294038 | 0.83 | S1PR1 (0.56) | ALDH1A1S1PR1S1PR3S1PR5S1PR4 | |
| SCHEMBL22363289 | 0.83 | S1PR1 (0.56) | ALDH1A1S1PR1S1PR3S1PR5S1PR4 | |
| SCHEMBL28123239 | 0.83 | S1PR1 (0.56) | ALDH1A1S1PR1S1PR3S1PR5S1PR4 | |
| SCHEMBL9869886 | 0.81 | ALDH1A1 (0.53) | ALDH1A1CYP1A2 | |
| Fluoride SCHEMBL29251661 | 0.81 | S1PR1 (0.55) | ALDH1A1S1PR1S1PR3S1PR5S1PR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210292300-A1 | DIMETHOXYPHENYL SUBSTITUTED INDOLE COMPOUNDS AS TLR7, TLR8 OR TLR9 INHIBITORS | BRISTOL MYERS SQUIBB CO (US) | 2021-09-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210292300-A1 | DIMETHOXYPHENYL SUBSTITUTED INDOLE COMPOUNDS AS TLR7, TLR8 OR TLR9 INHIBITORS | TLR9, TLR7, TLR8 | ALDH1A1 3760/4885S1PR1 264/4885S1PR3 317/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.