Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.47 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.44 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.44 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.44 |
| ▸ | DGAT1 | O75907 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | IDO1 | P14902 | 2/20 | 0.38 |
| ▸ | TDO2 | P48775 | 1/20 | 0.38 |
| ▸ | KCNQ3 | O43525 | 2/20 | 0.38 |
| ▸ | KCNQ2 | O43526 | 2/20 | 0.38 |
| ▸ | KCNE1 | P15382 | 2/20 | 0.38 |
| ▸ | KCNQ1 | P51787 | 2/20 | 0.38 |
| ▸ | MDM4 | O15151 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.38 |
| ▸ | EGFR | P00533 | 1/20 | 0.38 |
| ▸ | BACE1 | P56817 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22415211 | 0.80 | DGAT1 (0.46) | NAPRTADRA2AADRA2BADRA2CDGAT1 | |
| SCHEMBL1726659 | 0.79 | NAPRT (0.52) | NAPRTADRA2AADRA2BADRA2CDGAT1 | |
| SCHEMBL1726660 | 0.79 | NAPRT (0.52) | NAPRTADRA2AADRA2BADRA2CDGAT1 | |
| SCHEMBL17778492 | 0.79 | NAPRT (0.52) | NAPRTADRA2AADRA2BADRA2CDGAT1 | |
| SCHEMBL30515503 | 0.79 | NAPRT (0.52) | NAPRTADRA2AADRA2BADRA2CDGAT1 | |
| SCHEMBL23845464 | 0.79 | NAPRT (0.52) | NAPRTADRA2AADRA2BADRA2CDGAT1 | |
| SCHEMBL13342190 | 0.79 | NAPRT (0.52) | NAPRTADRA2AADRA2BADRA2CDGAT1 | |
| SCHEMBL23845527 | 0.79 | NNMT (0.42) | ADRA2AADRA2BADRA2CTDP1GAA | |
| SCHEMBL23212891 | 0.78 | KDM4E (0.47) | NAPRTADRA2AADRA2BADRA2CRAB9A | |
| SCHEMBL23212893 | 0.78 | KDM4E (0.47) | NAPRTADRA2AADRA2BADRA2CRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3257851-B1 | SALT FORM AND CRYSTAL FORM OF 1,2,5 THIADIAZOLIDIN-1,1-DIOXIDE, PREPARATION METHOD THEREOF AND INTERMEDIATE | JIANGSU KANION PHARMACEUTICAL CO LTD (CN) | 2020-09-09 | — | — | EP | disclosed |
| EP-3257851-A1 | SALT FORM AND CRYSTAL FORM OF 1,2,5 THIADIAZOLIDIN-1,1-DIOXIDE, PREPARATION METHOD THEREOF AND INTERMEDIATE | Jiangsu Kanion Pharmaceutical Co., Ltd. (CN) | 2017-12-20 | — | — | EP | disclosed |