SCHEMBL23847351

SCHEMBL23847351

NC(=O)Nc1ccc2c(c1)Cc1ccccc1O2

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOA P21397 3/20 0.50
MAOB P27338 1/20 0.50
CYP1A2 P05177 2/20 0.44
ADRA2A P08913 1/20 0.44
SLC6A2 P23975 1/20 0.44
HTR2C P28335 1/20 0.44
SLC6A4 P31645 1/20 0.44
HTR2B P41595 1/20 0.44
ACSL1 P33121 1/20 0.44
GAA P10253 1/20 0.42
MAPT P10636 1/20 0.42
GFER P55789 1/20 0.42
RAB9A P51151 5/20 0.42
SMN1; SMN2 Q16637 2/20 0.42
CASP3 P42574 1/20 0.42
SENP7 Q9BQF6 1/20 0.42
SENP6 Q9GZR1 1/20 0.42
L3MBTL1 Q9Y468 1/20 0.42
NPC1 O15118 3/20 0.41
TP53 P04637 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27851901 0.75 MAOA (0.47) MAOAMAOBGAAMAPTRAB9A
SCHEMBL10845751 0.74 MAOA (0.55) MAOAMAOBCYP1A2ACSL1MAPT
SCHEMBL27736976 0.73 MAOA (0.59) MAOAMAOBACSL1MAPTRAB9A
Xanthene SCHEMBL27837879 0.73 MAOA (0.85) MAOAMAOBCYP1A2ACSL1GAA
SCHEMBL9698365 0.72 MAOA (0.57) MAOAMAOBACSL1MAPTRAB9A
SCHEMBL29429630 0.72 SRD5A2 (0.58) MAOAMAOBACSL1MAPK1TDP1
SCHEMBL6621488 0.72 SRD5A2 (0.58) MAOAMAOBACSL1MAPK1TDP1
SCHEMBL11814250 0.71 PTGS1 (0.54) MAOAMAOBACSL1
Xanthene SCHEMBL28833627 0.71 MAOA (0.61) MAOAMAOBACSL1GAARAB9A
SCHEMBL9455528 0.71 MAOA (0.81) MAOAMAOBACSL1GAARAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210293765-A1 DETECTION REAGENT, DETECTION DEVICE, AND METHOD FOR DETECTING PRIMARY AMIDE COMPOUND INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE (TW) 2021-09-23 US disclosed