SCHEMBL23848857

SCHEMBL23848857

C=NNc1ccccc1NC

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
POLB P06746 3/20 0.43
KDM4E B2RXH2 2/20 0.43
MAPT P10636 2/20 0.43
TDP1 Q9NUW8 2/20 0.43
L3MBTL1 Q9Y468 2/20 0.43
ALDH1A1 P00352 2/20 0.43
RECQL P46063 2/20 0.43
USP2 O75604 1/20 0.43
HPGD P15428 1/20 0.43
NPSR1 Q6W5P4 1/20 0.43
HSD17B10 Q99714 1/20 0.43
ATM Q13315 1/20 0.36
SMN1; SMN2 Q16637 2/20 0.35
EGFR P00533 1/20 0.35
PABPC1 P11940 1/20 0.35
MAPK1 P28482 1/20 0.35
RAB9A P51151 1/20 0.35
HTR6 P50406 1/20 0.35
TSHR P16473 1/20 0.35
IDO1 P14902 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL653948 0.79 POLB (0.60) POLBKDM4EMAPTTDP1L3MBTL1
SCHEMBL29449705 0.79 POLB (0.60) POLBKDM4EMAPTTDP1L3MBTL1
SCHEMBL18137930 0.76 MAPT (0.48) POLBKDM4EMAPTTDP1ALDH1A1
SCHEMBL15782782 0.76 POLB (0.43) POLBKDM4EMAPTTDP1L3MBTL1
Hydrochloric Acid SCHEMBL30384582 0.76 MAPT (0.57) POLBKDM4EMAPTTDP1L3MBTL1
SCHEMBL30484919 0.76 POLB (0.57) POLBKDM4EMAPTTDP1L3MBTL1
SCHEMBL1096366 0.71 MAPT (0.48) POLBKDM4EMAPTTDP1ALDH1A1
SCHEMBL25078194 0.71 RAB9A (0.45) POLBALDH1A1SMN1; SMN2RAB9AMEN1
SCHEMBL14304537 0.71 GAA (0.46) KDM4EMAPTTDP1L3MBTL1ALDH1A1
SCHEMBL8521796 0.71 POLB (0.43) POLBKDM4EMAPTTDP1L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2021186308-A1 LUBRICATING OIL COMPOSITIONS FOR AUTOMATIC TRANSMISSIONS CHEVRON JAPAN LTD. (JP) 2021-09-23 WO disclosed