Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | NOTUM | Q6P988 | 3/20 | 0.43 |
| ▸ | NAMPT | P43490 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | NR1H2 | P55055 | 2/20 | 0.40 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.38 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.38 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.38 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25508997 | 0.83 | MAPK1 (0.43) | MAPK1NOTUMNAMPTMAPTMEN1 | |
| SCHEMBL23849027 | 0.77 | NOTUM (0.56) | MAPK1NOTUMMAPTMEN1KMT2A | |
| SCHEMBL25509005 | 0.75 | BACE1 (0.46) | NOTUM | |
| SCHEMBL23849032 | 0.75 | NOTUM (0.48) | MAPK1NOTUMMAPTMEN1KMT2A | |
| SCHEMBL15522954 | 0.73 | MEN1 (0.55) | MAPK1NOTUMNAMPTMEN1KMT2A | |
| SCHEMBL21505062 | 0.72 | MAPK1 (0.59) | MAPK1NAMPTMAPTNR1H2GPR119 | |
| SCHEMBL6615609 | 0.71 | FNTA (0.50) | MAPK1NAMPTLIPG | |
| SCHEMBL5849947 | 0.71 | MAPK1 (0.52) | MAPK1NAMPTMAPTMEN1KMT2A | |
| SCHEMBL20957003 | 0.71 | DRD2 (0.58) | MAPK1NOTUMMAPTMEN1KMT2A | |
| SCHEMBL15523452 | 0.70 | MAPK1 (0.48) | MAPK1NAMPTMEN1KMT2ANR1H2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021188620-A1 | PEPTIDOMIMETIC N5-METHYL-N2-(NONANOYL-L-LEUCYL)-L-GLUTAMINATE DERIVATIVES, TRIAZASPIRO[4.14]NONADECANE DERIVATIVES AND SIMILAR COMPOUNDS AS INHIBITORS OF NOROVIRUS AND CORONAVIRUS REPLICATION | COCRYSTAL PHARMA INC. (US) | 2021-09-23 | — | — | WO | disclosed |