Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 6/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 4/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 3/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23849027 | 0.82 | NOTUM (0.56) | NOTUMTSHRMAPTMEN1KMT2A | |
| SCHEMBL25508267 | 0.81 | NOTUM (0.47) | NOTUMTSHRMAPTMEN1KMT2A | |
| SCHEMBL25517743 | 0.81 | NOTUM (0.60) | NOTUMTSHRMAPTMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL30420089 | 0.81 | NOTUM (0.46) | NOTUMTSHRMAPTMEN1KMT2A | |
| SCHEMBL25428603 | 0.77 | TSHR (0.49) | NOTUMTSHRMAPTMEN1KMT2A | |
| SCHEMBL23849039 | 0.75 | MAPK1 (0.44) | NOTUMTSHRMAPTMEN1KMT2A | |
| SCHEMBL23833982 | 0.74 | ALDH1A1 (0.49) | NOTUMTSHRMAPTMEN1KMT2A | |
| SCHEMBL25517747 | 0.73 | MAPT (0.53) | NOTUMTSHRMAPTMEN1KMT2A | |
| SCHEMBL25508275 | 0.73 | CTSL (0.42) | NOTUMTSHR | |
| Hydrochloric Acid SCHEMBL23833985 | 0.73 | ALDH1A1 (0.48) | NOTUMTSHRMAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021188620-A1 | PEPTIDOMIMETIC N5-METHYL-N2-(NONANOYL-L-LEUCYL)-L-GLUTAMINATE DERIVATIVES, TRIAZASPIRO[4.14]NONADECANE DERIVATIVES AND SIMILAR COMPOUNDS AS INHIBITORS OF NOROVIRUS AND CORONAVIRUS REPLICATION | COCRYSTAL PHARMA INC. (US) | 2021-09-23 | — | — | WO | disclosed |