Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1244882 | 0.71 | ALDH1A1 (0.37) | ALDH1A1 | |
| SCHEMBL1244609 | 0.71 | ALDH1A1 (0.37) | ALDH1A1 | |
| SCHEMBL989882 | 0.71 | ALDH1A1 (0.37) | ALDH1A1 | |
| SCHEMBL4961745 | 0.71 | ALDH1A1 (0.30) | ALDH1A1 | |
| Tetranitrin SCHEMBL16541075 | 0.70 | ALDH1A1 (0.40) | ALDH1A1 | |
| Erythrityl Tetranitrate SCHEMBL1816345 | 0.70 | ALDH1A1 (0.40) | ALDH1A1 | |
| Nitroglycerin SCHEMBL15421 | 0.70 | PTGS2 (0.40) | ALDH1A1 | |
| Erythrityl Tetranitrate SCHEMBL119876 | 0.70 | ALDH1A1 (0.40) | ALDH1A1 | |
| Tetranitrin SCHEMBL613474 | 0.70 | ALDH1A1 (0.40) | ALDH1A1 | |
| Nitroglycerin SCHEMBL920644 | 0.70 | PTGS2 (0.40) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021231582-A1 | NITRO-AMINOADAMANTANE COMPOUNDS FOR THE TREATMENT OF NEGATIVE SYMPTOMS AND COGNITIVE IMPAIRMENT ASSOCIATED WITH SCHIZOPHRENIA | EUMENTIS THERAPEUTICS, INC. (US) | 2021-11-18 | — | — | WO | disclosed |
| WO-2021188864-A1 | NITRO-AMINOADAMANTANE COMPOUNDS FOR THE TREATMENT OF BETACORONAVIRUS INFECTIONS | EUMENTIS THERAPEUTICS, INC. (US) | 2021-09-23 | — | — | WO | disclosed |