Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 2/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.33 |
| ▸ | PLG | P00747 | 3/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | NSD3 | Q9BZ95 | 1/20 | 0.31 |
| ▸ | HTR2A | P28223 | 3/20 | 0.31 |
| ▸ | HTR2C | P28335 | 3/20 | 0.31 |
| ▸ | HTR2B | P41595 | 2/20 | 0.31 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.31 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.31 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | PKM | P14618 | 1/20 | 0.30 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23849717 | 1.00 | SLC6A2 (0.33) | SLC6A2SLC6A4SLC6A3PLGTP53 | |
| SCHEMBL17001769 | 0.82 | PLG (0.34) | SLC6A2SLC6A4SLC6A3PLGTP53 | |
| SCHEMBL17001786 | 0.82 | PLG (0.34) | SLC6A2SLC6A4SLC6A3PLGTP53 | |
| SCHEMBL18444558 | 0.82 | PLG (0.34) | SLC6A2SLC6A4SLC6A3PLGTP53 | |
| SCHEMBL11229667 | 0.79 | LMNA (0.41) | MEN1KMT2A | |
| SCHEMBL14334701 | 0.76 | MEN1 (0.33) | SLC6A2SLC6A4SLC6A3PLGTP53 | |
| SCHEMBL18477427 | 0.76 | TP53 (0.32) | TP53GABRA1GABRG2GABRB3 | |
| SCHEMBL18438184 | 0.76 | TP53 (0.32) | TP53GABRA1GABRG2GABRB3 | |
| Acetic Acid SCHEMBL20292256 | 0.75 | KMT2A (0.36) | PLGNSD3GABRA1GABRG2GABRB3 | |
| Acetic Acid SCHEMBL16992490 | 0.75 | KMT2A (0.36) | PLGNSD3GABRA1GABRG2GABRB3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3331529-B1 | MUSCARINIC AGONISTS | HEPTARES THERAPEUTICS LTD (GB) | 2021-09-29 | — | — | EP | disclosed |