Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.40 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | GSK3A | P49840 | 1/20 | 0.36 |
| ▸ | GSK3B | P49841 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3287190 | 0.84 | MAPK1 (0.38) | LMNAOPRM1OPRL1MAPK1POLB | |
| SCHEMBL2991774 | 0.81 | HTT (0.43) | LMNAPOLBGAAGSK3AGSK3B | |
| SCHEMBL4681766 | 0.81 | HTT (0.43) | LMNAPOLBGAAGSK3AGSK3B | |
| SCHEMBL23849717 | 0.79 | SLC6A2 (0.33) | KMT2AMEN1 | |
| SCHEMBL23849709 | 0.79 | SLC6A2 (0.33) | KMT2AMEN1 | |
| SCHEMBL4681145 | 0.78 | HTT (0.41) | GSK3AGSK3BKMT2A | |
| SCHEMBL20465791 | 0.75 | — | — | |
| SCHEMBL20465784 | 0.75 | — | — | |
| SCHEMBL20465788 | 0.75 | — | — | |
| SCHEMBL11077004 | 0.73 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-57159758-A | — | — | None | — | — | JP | disclosed |
| JP-S57159758-A | PREPARATION OF BETA-LACTAM | NIPPON CHEMIPHAR CO LTD | 1982-10-01 | — | — | JP | disclosed |