Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 5/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 3/20 | 0.47 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.47 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | CTPS1 | P17812 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | ALDH1A3 | P47895 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31587565 | 1.00 | MAPT (0.58) | MAPTMAPK1TDP1ALDH1A1KMT2A | |
| SCHEMBL23851510 | 0.88 | MAPT (0.59) | MAPTMAPK1TDP1ALDH1A1KMT2A | |
| SCHEMBL20524573 | 0.87 | MAPT (0.62) | MAPTMAPK1TDP1ALDH1A1KMT2A | |
| SCHEMBL28799327 | 0.84 | MAPT (0.55) | MAPTMAPK1TDP1ALDH1A1KMT2A | |
| SCHEMBL23850391 | 0.83 | ALDH1A1 (0.65) | MAPTMAPK1TDP1ALDH1A1VCAM1 | |
| SCHEMBL31587859 | 0.83 | ALDH1A1 (0.65) | MAPTMAPK1TDP1ALDH1A1VCAM1 | |
| SCHEMBL28867034 | 0.81 | MAPT (0.60) | MAPTMAPK1TDP1ALDH1A1KMT2A | |
| SCHEMBL23850819 | 0.81 | MAPT (0.72) | MAPTMAPK1ALDH1A1KMT2AMEN1 | |
| SCHEMBL31587566 | 0.81 | MAPT (0.72) | MAPTMAPK1ALDH1A1KMT2AMEN1 | |
| SCHEMBL14335232 | 0.80 | MAPT (0.54) | MAPTMAPK1TDP1ALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12485169-B2 | Compounds | Grey Wolf Therapeutics Limited (GB) | 2025-12-02 | — | — | US | disclosed |
| US-20230064417-A1 | COMPOUNDS | Grey Wolf Therapeutics Limited (GB) | 2023-03-02 | — | — | US | disclosed |
| EP-3883650-A1 | COMPOUNDS | Grey Wolf Therapeutics Limited (GB) | 2021-09-29 | — | — | EP | disclosed |
| CN-113056305-A | Compound (I) | 格雷沃尔夫治疗有限公司 | 2021-06-29 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230064417-A1 | COMPOUNDS | H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16, HRH4, CBR3 | MAPT 4705/4885MAPK1 4309/4885TDP1 4857/4885 |
| US-12485169-B2 | Compounds | SLC10A1, VHL, CFTR | MAPT 302/4885MAPK1 1915/4885TDP1 1403/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.