Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 4/20 | 0.41 |
| ▸ | HPGD | P15428 | 3/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.39 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.38 |
| ▸ | AMY1A | P0DUB6 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.33 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.33 |
| ▸ | GFER | P55789 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27721625 | 0.80 | L3MBTL1 (0.38) | KMT2AL3MBTL1KDM4ELMNAHPGD | |
| SCHEMBL5764749 | 0.79 | KMT2A (0.54) | KMT2AL3MBTL1KDM4ELMNAHPGD | |
| SCHEMBL18490047 | 0.79 | KMT2A (0.54) | KMT2AL3MBTL1KDM4ELMNAHPGD | |
| SCHEMBL18502970 | 0.79 | AMY1A (0.59) | KMT2AL3MBTL1KDM4ELMNAHPGD | |
| SCHEMBL8692623 | 0.79 | AMY1A (0.59) | KMT2AL3MBTL1KDM4ELMNAHPGD | |
| SCHEMBL8692626 | 0.79 | AMY1A (0.59) | KMT2AL3MBTL1KDM4ELMNAHPGD | |
| SCHEMBL27721812 | 0.76 | L3MBTL1 (0.38) | KMT2AL3MBTL1KDM4ELMNAHPGD | |
| SCHEMBL27527755 | 0.76 | L3MBTL1 (0.38) | KMT2AL3MBTL1KDM4ELMNAHPGD | |
| SCHEMBL24861816 | 0.76 | CYP1A1 (0.42) | CYP1A1CYP1A2CYP1B1TAAR1AMY1A | |
| SCHEMBL23850354 | 0.76 | ERN1 (0.47) | L3MBTL1KDM4ELMNACYP1A1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3883925-A1 | CYCLIC UREAS | Sironax Ltd (KY) | 2021-09-29 | — | — | EP | disclosed |