Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | FFAR2 | O15552 | 5/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | XPO1 | O14980 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | CASP6 | P55212 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | APP | P05067 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | KCNQ3 | O43525 | 1/20 | 0.30 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.30 |
| ▸ | KCNE1 | P15382 | 1/20 | 0.30 |
| ▸ | KCNQ1 | P51787 | 1/20 | 0.30 |
| ▸ | KCNQ5 | Q9NR82 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1554935 | 0.75 | SMN1; SMN2 (0.40) | SMN1; SMN2ALDH1A1GAAPOLBCASP6 | |
| SCHEMBL12413632 | 0.75 | SMN1; SMN2 (0.42) | SMN1; SMN2ALDH1A1GAAPOLBCASP6 | |
| SCHEMBL28182534 | 0.72 | ALDH1A1 (0.40) | ALDH1A1L3MBTL1KMT2A | |
| SCHEMBL30463142 | 0.72 | ALDH1A1 (0.40) | ALDH1A1L3MBTL1KMT2A | |
| SCHEMBL28182535 | 0.72 | ALDH1A1 (0.40) | ALDH1A1L3MBTL1KMT2A | |
| SCHEMBL30577163 | 0.72 | SMN1; SMN2 (0.44) | SMN1; SMN2ALDH1A1GAAPOLBCASP6 | |
| SCHEMBL5335551 | 0.72 | SMN1; SMN2 (0.44) | SMN1; SMN2ALDH1A1GAAPOLBCASP6 | |
| SCHEMBL23850565 | 0.71 | KMT2A (0.45) | SMN1; SMN2FFAR2KMT2A | |
| SCHEMBL20165502 | 0.71 | MAPK1 (0.49) | SMN1; SMN2ALDH1A1GAAXPO1POLB | |
| SCHEMBL16885200 | 0.69 | MAPT (0.40) | SMN1; SMN2ALDH1A1GAAPOLBCASP6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3883925-A1 | CYCLIC UREAS | Sironax Ltd (KY) | 2021-09-29 | — | — | EP | disclosed |