Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LRRK2 | Q5S007 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | IRAK4 | Q9NWZ3 | 2/20 | 0.38 |
| ▸ | S100B | P04271 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.36 |
| ▸ | MAP3K12 | Q12852 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31587963 | 1.00 | LRRK2 (0.41) | LRRK2ALDH1A1HTTGAAL3MBTL1 | |
| SCHEMBL249165 | 0.83 | PDE3B (0.43) | LRRK2ALDH1A1L3MBTL1SLC6A9KCNH2 | |
| SCHEMBL31587548 | 0.83 | LRRK2 (0.45) | LRRK2ALDH1A1HTTGAAL3MBTL1 | |
| SCHEMBL23851021 | 0.83 | LRRK2 (0.45) | LRRK2ALDH1A1HTTGAAL3MBTL1 | |
| SCHEMBL3085427 | 0.81 | S100B (0.59) | ALDH1A1HTTGAAL3MBTL1S100B | |
| SCHEMBL30668900 | 0.81 | LRRK2 (0.36) | LRRK2ALDH1A1SLC6A9KCNH2IRAK4 | |
| SCHEMBL31588227 | 0.80 | GAA (0.41) | LRRK2ALDH1A1HTTGAAL3MBTL1 | |
| SCHEMBL23851980 | 0.80 | GAA (0.41) | LRRK2ALDH1A1HTTGAAL3MBTL1 | |
| SCHEMBL13354909 | 0.80 | DRD2 (0.53) | ALDH1A1S100BKDM4EMAPTSMN1; SMN2 | |
| SCHEMBL1968214 | 0.79 | PDE3B (0.46) | LRRK2SLC6A9KCNH2IRAK4MAP3K12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12485169-B2 | Compounds | Grey Wolf Therapeutics Limited (GB) | 2025-12-02 | — | — | US | disclosed |
| US-20230064417-A1 | COMPOUNDS | Grey Wolf Therapeutics Limited (GB) | 2023-03-02 | — | — | US | disclosed |
| EP-3883650-A1 | COMPOUNDS | Grey Wolf Therapeutics Limited (GB) | 2021-09-29 | — | — | EP | disclosed |
| CN-113056305-A | Compound (I) | 格雷沃尔夫治疗有限公司 | 2021-06-29 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230064417-A1 | COMPOUNDS | H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16, HRH4, CBR3 | LRRK2 1016/4885ALDH1A1 2613/4885HTT 297/4885 |
| US-12485169-B2 | Compounds | SLC10A1, VHL, CFTR | LRRK2 1301/4885ALDH1A1 276/4885HTT 218/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.