Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.57 |
| ▸ | LMNA | P02545 | 2/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | IDH2 | P48735 | 8/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | PLA2G7 | Q13093 | 2/20 | 0.46 |
| ▸ | MGLL | Q99685 | 2/20 | 0.46 |
| ▸ | ABHD6 | Q9BV23 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | LIPG | Q9Y5X9 | 3/20 | 0.42 |
| ▸ | LPL | P06858 | 1/20 | 0.42 |
| ▸ | PDE3B | Q13370 | 2/20 | 0.42 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31588171 | 1.00 | ALDH1A1 (0.57) | ALDH1A1LMNAKDM4EMAPTMEN1 | |
| SCHEMBL23851042 | 1.00 | ALDH1A1 (0.57) | ALDH1A1LMNAKDM4EMAPTMEN1 | |
| SCHEMBL31588073 | 0.92 | LMNA (0.65) | ALDH1A1LMNAKDM4EMAPTMEN1 | |
| SCHEMBL31587375 | 0.92 | LMNA (0.65) | ALDH1A1LMNAKDM4EMAPTMEN1 | |
| SCHEMBL23850803 | 0.92 | LMNA (0.65) | ALDH1A1LMNAKDM4EMAPTMEN1 | |
| SCHEMBL23850683 | 0.92 | LMNA (0.65) | ALDH1A1LMNAKDM4EMAPTMEN1 | |
| SCHEMBL23850685 | 0.92 | LMNA (0.65) | ALDH1A1LMNAKDM4EMAPTMEN1 | |
| SCHEMBL31588198 | 0.88 | ALDH1A1 (0.59) | ALDH1A1LMNAKDM4EMAPTMEN1 | |
| SCHEMBL23850602 | 0.88 | ALDH1A1 (0.59) | ALDH1A1LMNAKDM4EMAPTMEN1 | |
| SCHEMBL1410343 | 0.84 | LMNA (0.55) | ALDH1A1LMNAMAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3883650-A1 | COMPOUNDS | Grey Wolf Therapeutics Limited (GB) | 2021-09-29 | — | — | EP | disclosed |
| CN-113056305-A | Compound (I) | 格雷沃尔夫治疗有限公司 | 2021-06-29 | — | — | CN | disclosed |