Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.65 |
| ▸ | HPGD | P15428 | 3/20 | 0.65 |
| ▸ | GLA | P06280 | 2/20 | 0.65 |
| ▸ | MAPT | P10636 | 2/20 | 0.65 |
| ▸ | ACHE | P22303 | 1/20 | 0.65 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.48 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.48 |
| ▸ | HTR3A | P46098 | 1/20 | 0.48 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.46 |
| ▸ | NQO2 | P16083 | 1/20 | 0.44 |
| ▸ | EGFR | P00533 | 1/20 | 0.43 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.43 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acridine SCHEMBL1041524 | 0.89 | MAPT (0.62) | ALDH1A1HPGDGLAMAPTACHE | |
| SCHEMBL255425 | 0.89 | CLK1 (0.48) | ALDH1A1HPGDGLAMAPTACHE | |
| SCHEMBL4113492 | 0.87 | MAPT (0.65) | ALDH1A1HPGDGLAMAPTACHE | |
| SCHEMBL30520081 | 0.84 | CLK1 (0.47) | ALDH1A1HPGDGLAMAPTACHE | |
| SCHEMBL9392287 | 0.84 | ALDH1A1 (0.56) | ALDH1A1HPGDGLAMAPTACHE | |
| SCHEMBL9394403 | 0.84 | ALDH1A1 (0.56) | ALDH1A1HPGDGLAMAPTACHE | |
| SCHEMBL20272949 | 0.82 | CLK1 (0.53) | ALDH1A1HPGDGLAMAPTACHE | |
| Acridine SCHEMBL28260005 | 0.81 | ALDH1A1 (0.79) | ALDH1A1HPGDGLAMAPTACHE | |
| Acridine SCHEMBL1772714 | 0.81 | ALDH1A1 (1.00) | ALDH1A1HPGDGLAMAPTACHE | |
| Acridine SCHEMBL8339 | 0.81 | ALDH1A1 (1.00) | ALDH1A1HPGDGLAMAPTACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 48 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-121135709-A | Benzo [ b ] [1,6] naphthyridine compound and preparation method and application thereof | 河北科技大学 | 2025-12-16 | — | — | CN | disclosed |
| CN-121135709-A | Benzo [ b ] [1,6] naphthyridine compound and preparation method and application thereof | 河北科技大学 | 2025-12-16 | — | — | CN | disclosed |
| EP-3386508-B1 | CPAP-TUBULIN MODULE | UNIV KOELN (DE) | 2025-04-16 | — | — | EP | disclosed |
| US-11851427-B2 | Phosphodiesterase inhibitors and uses thereof | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 2023-12-26 | — | — | US | disclosed |
| US-20210130349-A1 | NOVEL PHOSPHODIESTERASE INHIBITORS AND USES THEREOF | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK | 2021-05-06 | — | — | US | disclosed |
| US-10899756-B2 | Phosphodiesterase inhibitors and uses thereof | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 2021-01-26 | — | — | US | disclosed |
| US-10875856-B2 | CPAP-tubulin module | UNIVERSITAET ZU KOELN (DE) | 2020-12-29 | — | — | US | disclosed |
| US-10626113-B2 | Phosphodiesterase inhibitors and uses thereof | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 2020-04-21 | — | — | US | disclosed |
| EP-3022205-B1 | NOVEL PHOSPHODIESTERASE INHIBITORS AND USES THEREOF | UNIV COLUMBIA (US) | 2020-02-05 | — | — | EP | disclosed |
| US-20180362527-A1 | CPAP-TUBULIN MODULE | UNIVERSITAET ZU KOELN (DE) | 2018-12-20 | — | — | US | disclosed |
| US-7498331-B2 | Arthropod repellent pharmacophore models, compounds identified as fitting the pharmacophore models, and methods of making and using thereof | UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE ARMY (US) | 2009-03-03 | — | — | US | disclosed |
| WO-2008130515-A1 | ANTI-CANCER AGENTS, COMPOSITIONS AND METHODS OF TREATING CANCERS | ACB, LLC (US) | 2008-10-30 | — | — | WO | disclosed |
| EP-1392289-A2 | CASPASE INHIBITORS AND USES THEREOF | Vertex Pharmaceuticals Incorporated (US) | 2004-03-03 | — | — | EP | disclosed |
| WO-2002094263-A2 | CASPASE INHIBITORS AND USES THEREOF | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2002-11-28 | — | — | WO | disclosed |
| EP-1142892-A1 | PROCESSES FOR THE PREPARATION OF NOVEL NAPHTHYRIDINE DERIVATIVES | Nippon Kayaku Kabushiki Kaisha (JP) | 2001-10-10 | — | — | EP | disclosed |
| US-4816464-A | ANTIINFLAMMATORY AGENTS, ENZYME TISSUE DESTRUCTION | AMERICAN HOME PRODUCTS CORPORATION (US) | 1989-03-28 | — | — | US | disclosed |
| US-4816464-A | ANTIINFLAMMATORY AGENTS, ENZYME TISSUE DESTRUCTION | AMERICAN HOME PRODUCTS CORPORATION (US) | 1989-03-28 | — | — | US | disclosed |
| US-4808612-A | ANTIINFLAMMATORY AGENTS | AMERICAN HOME PRODUCTS CORPORATION (US) | 1989-02-28 | — | — | US | disclosed |
| US-4751305-A | ANTIINFLAMMATORY AGENTS | AMERICAN HOME PRODUCTS CORPORATION (US) | 1988-06-14 | — | — | US | disclosed |
| US-4748246-A | INTERLEUKIN ANTAGONISTS, ANTIINFLAMMATORY AGENTS | AMERICAN HOME PRODUCTS CORPORATION (US) | 1988-05-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11851427-B2 | Phosphodiesterase inhibitors and uses thereof | PDE5A, PDE2A, PDE3A | ALDH1A1 1252/4885HPGD 377/4885GLA 448/4885 |
| US-10875856-B2 | CPAP-tubulin module | TUBB1, TUBA1C, TUBB | ALDH1A1 3356/4885HPGD 4769/4885GLA 1610/4885 |
| US-10899756-B2 | Phosphodiesterase inhibitors and uses thereof | PDE5A, PDE2A, PDE3A | ALDH1A1 1252/4885HPGD 377/4885GLA 448/4885 |
| US-10626113-B2 | Phosphodiesterase inhibitors and uses thereof | PDE5A, PDE2A, PDE3A | ALDH1A1 1252/4885HPGD 377/4885GLA 448/4885 |
| US-20210130349-A1 | NOVEL PHOSPHODIESTERASE INHIBITORS AND USES THEREOF | PDE5A, PDE2A, PDE3A | ALDH1A1 1375/4885HPGD 477/4885GLA 438/4885 |
| US-20180362527-A1 | CPAP-TUBULIN MODULE | TUBB1, TUBA1C, TUBB | ALDH1A1 3356/4885HPGD 4769/4885GLA 1610/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.