Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA1A | P35348 | 12/20 | 0.55 |
| ▸ | HRH3 | Q9Y5N1 | 5/20 | 0.44 |
| ▸ | TYRO3 | Q06418 | 3/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31047833 | 0.87 | ADRA1A (0.54) | ADRA1AHRH3 | |
| SCHEMBL16855417 | 0.87 | ADRA1A (0.54) | ADRA1AHRH3 | |
| SCHEMBL18186145 | 0.84 | ADRA1A (0.57) | ADRA1AHRH3 | |
| SCHEMBL31047863 | 0.78 | ADRA1A (0.65) | ADRA1A | |
| SCHEMBL16855368 | 0.78 | ADRA1A (0.65) | ADRA1A | |
| SCHEMBL31047818 | 0.76 | ADRA1A (0.67) | ADRA1A | |
| SCHEMBL16855473 | 0.76 | ADRA1A (0.67) | ADRA1A | |
| SCHEMBL31047821 | 0.75 | ADRA1A (0.80) | ADRA1A | |
| SCHEMBL16855302 | 0.75 | ADRA1A (0.80) | ADRA1A | |
| SCHEMBL16855256 | 0.75 | ADRA1A (0.61) | ADRA1AHRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3883933-A1 | a2-ADRENOCEPTOR SUBTYPE C (ALPHA-2C) ANTAGONISTS FOR THE TREATMENT OF SLEEP APNEA | Bayer Aktiengesellschaft (DE) | 2021-09-29 | — | — | EP | disclosed |