Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA1A | P35348 | 15/20 | 0.54 |
| ▸ | HRH3 | Q9Y5N1 | 5/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16855417 | 1.00 | ADRA1A (0.54) | ADRA1AHRH3 | |
| SCHEMBL18186145 | 0.97 | ADRA1A (0.57) | ADRA1AHRH3 | |
| SCHEMBL16855368 | 0.91 | ADRA1A (0.65) | ADRA1A | |
| SCHEMBL31047863 | 0.91 | ADRA1A (0.65) | ADRA1A | |
| SCHEMBL31047818 | 0.89 | ADRA1A (0.67) | ADRA1A | |
| SCHEMBL16855473 | 0.89 | ADRA1A (0.67) | ADRA1A | |
| SCHEMBL23852178 | 0.87 | ADRA1A (0.55) | ADRA1AHRH3 | |
| SCHEMBL16855256 | 0.87 | ADRA1A (0.61) | ADRA1AHRH3 | |
| SCHEMBL16855418 | 0.80 | ADRA1A (0.81) | ADRA1A | |
| SCHEMBL18186150 | 0.75 | ADRA1A (0.52) | ADRA1AHRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113166166-B | Alpha 2-adrenoreceptor subtype C (alpha-2C) antagonists for the treatment of sleep apnea | 拜耳公司 | 2024-09-10 | — | — | CN | disclosed |