Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | AURKA | O14965 | 1/20 | 0.40 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 4/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | KCNH3 | Q9ULD8 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | GBA1 | P04062 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30002422 | 0.81 | HPGD (0.50) | ALDH1A1NPC1HPGDKDM4EHSD17B10 | |
| SCHEMBL29668628 | 0.81 | HPGD (0.50) | ALDH1A1NPC1HPGDKDM4EHSD17B10 | |
| SCHEMBL29668727 | 0.77 | KDM4E (0.65) | ALDH1A1NPC1HPGDKDM4EHSD17B10 | |
| SCHEMBL4536599 | 0.77 | KMT2A (0.47) | ALDH1A1NPC1AURKARPS6KB1HPGD | |
| SCHEMBL30233310 | 0.76 | KCNH3 (0.44) | ALDH1A1NPC1HPGDKDM4EHSD17B10 | |
| SCHEMBL28963497 | 0.71 | KDM4E (0.74) | ALDH1A1NPC1HPGDKDM4EHSD17B10 | |
| SCHEMBL20797890 | 0.70 | KCNH3 (0.55) | ALDH1A1NPC1HPGDKDM4EKCNH3 | |
| SCHEMBL23852691 | 0.70 | KDM4E (0.49) | ALDH1A1NPC1HPGDKDM4EHSD17B10 | |
| SCHEMBL1962657 | 0.70 | KCNH3 (0.55) | ALDH1A1NPC1HPGDKDM4EKCNH3 | |
| SCHEMBL21501690 | 0.69 | KDM4E (0.56) | ALDH1A1HPGDKDM4EHSD17B10KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3883928-A1 | GLP-1R AGONISTS AND USES THEREOF | Qilu Regor Therapeutics Inc. (CN) | 2021-09-29 | — | — | EP | disclosed |