Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 5/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | HCAR3 | P49019 | 2/20 | 0.45 |
| ▸ | FABP4 | P15090 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.44 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.44 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.44 |
| ▸ | DHFR | P00374 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | MPO | P05164 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29668628 | 1.00 | HPGD (0.50) | HPGDALDH1A1HSD17B10KDM4EAGTR1 | |
| SCHEMBL29668727 | 0.84 | KDM4E (0.65) | HPGDALDH1A1HSD17B10KDM4ERAB9A | |
| SCHEMBL194971 | 0.81 | KDM4C (0.63) | HPGDALDH1A1HSD17B10KDM4EAGTR1 | |
| SCHEMBL23852182 | 0.81 | ALDH1A1 (0.40) | HPGDALDH1A1HSD17B10KDM4ERAB9A | |
| SCHEMBL1715784 | 0.81 | KDM4C (0.52) | HPGDALDH1A1HSD17B10KDM4EAGTR1 | |
| SCHEMBL28963497 | 0.78 | KDM4E (0.74) | HPGDALDH1A1HSD17B10KDM4EMEN1 | |
| SCHEMBL29668581 | 0.77 | HCAR3 (0.46) | HPGDALDH1A1KDM4EPOLBL3MBTL1 | |
| SCHEMBL11503155 | 0.77 | KDM4C (0.66) | HPGDALDH1A1HSD17B10KDM4EAGTR1 | |
| SCHEMBL29149719 | 0.75 | HCAR3 (0.57) | HPGDALDH1A1HSD17B10KDM4ERAB9A | |
| SCHEMBL29149715 | 0.75 | HCAR3 (0.57) | HPGDALDH1A1HSD17B10KDM4ERAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4073051-A1 | PROCESS AND INTERMEDIATE FOR THE PREPARATION OF OXETAN-2-YLMETHANAMINE | Eli Lilly and Company (US) | 2022-10-19 | — | — | EP | disclosed |