SCHEMBL23853059

SCHEMBL23853059

C=CCCC(NC(C)=O)(C(=O)NC(C)(C)C)C1CCN(C(=O)O)CC1

nearest known ligand 0.35

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23850028 0.94 LMNA (0.33) LMNA
SCHEMBL23850333 0.86 EPHX1 (0.39) SMN1; SMN2
SCHEMBL899873 0.86 LMNA (0.30) LMNA
SCHEMBL899330 0.86 EPHX1 (0.39) SMN1; SMN2
SCHEMBL899874 0.86 LMNA (0.30) LMNA
SCHEMBL20485606 0.86
SCHEMBL24210655 0.84 EPHX1 (0.34)
SCHEMBL10207356 0.83 CCR2 (0.30)
Hydrochloric Acid SCHEMBL895688 0.81 CCR2 (0.30)
SCHEMBL895141 0.80

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3883938-A1 INHIBITORS OF ARGINASE Praxis Biotech LLC (US) 2021-09-29 EP disclosed