Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR2 | P41597 | 7/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | BLM | P54132 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27881373 | 0.76 | SMN1; SMN2 (0.41) | SMN1; SMN2KDM4E | |
| SCHEMBL4413281 | 0.68 | SMN1; SMN2 (0.37) | SMN1; SMN2ALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL14249431 | 0.68 | POLB (0.39) | SMN1; SMN2ALDH1A1GAAKDM4EMEN1 | |
| SCHEMBL28550488 | 0.66 | LMNA (0.33) | SMN1; SMN2MEN1KMT2ABLMLMNA | |
| SCHEMBL18302606 | 0.66 | CA1 (0.37) | SMN1; SMN2GAAKDM4EL3MBTL1LMNA | |
| SCHEMBL9846779 | 0.66 | CA1 (0.37) | SMN1; SMN2GAAKDM4EL3MBTL1LMNA | |
| SCHEMBL8188820 | 0.66 | CCR2 (0.31) | CCR2 | |
| SCHEMBL11802065 | 0.65 | CRBN (0.50) | CCR2ALDH1A1GAAKDM4EL3MBTL1 | |
| SCHEMBL5960403 | 0.65 | CRBN (0.50) | CCR2ALDH1A1GAAKDM4EL3MBTL1 | |
| SCHEMBL9110121 | 0.65 | CRBN (0.50) | CCR2ALDH1A1GAAKDM4EL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3883647-A1 | C10-ALKYLENE SUBSTITUTED 13-MEMBERED MACROLIDES AND USES THEREOF | Zikani Therapeutics, Inc. (US) | 2021-09-29 | — | — | EP | disclosed |