Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRC | P12931 | 8/20 | 0.59 |
| ▸ | TEK | Q02763 | 6/20 | 0.59 |
| ▸ | LCK | P06239 | 6/20 | 0.59 |
| ▸ | KDR | P35968 | 4/20 | 0.59 |
| ▸ | EGFR | P00533 | 4/20 | 0.59 |
| ▸ | ABL1 | P00519 | 4/20 | 0.59 |
| ▸ | HCK | P08631 | 3/20 | 0.59 |
| ▸ | ERBB2 | P04626 | 2/20 | 0.59 |
| ▸ | ERBB4 | Q15303 | 2/20 | 0.59 |
| ▸ | BTK | Q06187 | 2/20 | 0.59 |
| ▸ | MAP4K4 | O95819 | 2/20 | 0.59 |
| ▸ | PAK4 | O96013 | 2/20 | 0.59 |
| ▸ | FYN | P06241 | 2/20 | 0.59 |
| ▸ | CSF1R | P07333 | 2/20 | 0.59 |
| ▸ | RET | P07949 | 2/20 | 0.59 |
| ▸ | FGFR1 | P11362 | 2/20 | 0.59 |
| ▸ | FLT1 | P17948 | 2/20 | 0.59 |
| ▸ | FLT3 | P36888 | 2/20 | 0.59 |
| ▸ | CSNK1A1 | P48729 | 2/20 | 0.59 |
| ▸ | LIMK1 | P53667 | 2/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23854924 | 1.00 | SRC (0.59) | SRCTEKLCKKDREGFR | |
| SCHEMBL17085734 | 0.90 | ADK (0.51) | SRCTEKLCKKDREGFR | |
| SCHEMBL18640804 | 0.87 | SRC (0.59) | SRCLCKKDREGFRABL1 | |
| SCHEMBL6867797 | 0.85 | SRC (0.59) | SRCTEKLCKKDREGFR | |
| SCHEMBL6866172 | 0.85 | SRC (0.59) | SRCTEKLCKKDREGFR | |
| SCHEMBL4721622 | 0.85 | SRC (0.59) | SRCTEKLCKKDREGFR | |
| Hydrochloric Acid SCHEMBL6868362 | 0.84 | SRC (0.58) | SRCTEKLCKKDREGFR | |
| Hydrochloric Acid SCHEMBL6868366 | 0.84 | SRC (0.58) | SRCTEKLCKKDREGFR | |
| SCHEMBL869590 | 0.82 | ADK (0.53) | SRCLCKKDREGFRABL1 | |
| SCHEMBL25612151 | 0.82 | SRC (0.61) | SRCTEKLCKKDREGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11963960-B2 | Compounds for treating or inhibiting recurrence of acute myeloid leukemia | FLASH THERAPEUTICS, LLC (US) | 2024-04-23 | — | — | US | disclosed |
| CN-115298180-A | Compounds for treating or inhibiting recurrence of acute myeloid leukemia | 富雷旭医疗有限责任公司 | 2022-11-04 | — | — | CN | disclosed |
| US-20210299128-A1 | COMPOUNDS FOR TREATING OR INHIBITING RECURRENCE OF ACUTE MYELOID LEUKEMIA | RIKEN (JP) | 2021-09-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11963960-B2 | Compounds for treating or inhibiting recurrence of acute myeloid leukemia | MCL1, FLT3, ABL1 | SRC 95/4885TEK 622/4885LCK 188/4885 |
| US-20210299128-A1 | COMPOUNDS FOR TREATING OR INHIBITING RECURRENCE OF ACUTE MYELOID LEUKEMIA | MCL1, FLT3, ABL1 | SRC 95/4885TEK 622/4885LCK 188/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.