SCHEMBL23855

SCHEMBL23855

Nc1ccc(-c2ccc(N)c(N)c2)cc1N

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 6/20 1.00
KMT2A Q03164 5/20 1.00
MEN1 O00255 4/20 1.00
KCNH2 Q12809 2/20 0.61
CYP3A4 P08684 8/20 0.55
ALDH1A1 P00352 7/20 0.55
ALOX15 P16050 6/20 0.55
HSD17B10 Q99714 5/20 0.55
TSHR P16473 4/20 0.55
MAPK1 P28482 2/20 0.52
CYP17A1 P05093 2/20 0.52
CYP19A1 P11511 2/20 0.52
CYP11B1 P15538 2/20 0.52
CYP11B2 P19099 2/20 0.52
SMN1; SMN2 Q16637 3/20 0.50
TP53 P04637 1/20 0.50
THRB P10828 1/20 0.50
NR4A1 P22736 1/20 0.48
PTK2 Q05397 1/20 0.47
KDM4E B2RXH2 4/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29349835 1.00 TDP1 (1.00) TDP1KMT2AMEN1KCNH2CYP3A4
SCHEMBL3497479 0.97 TDP1 (0.93) TDP1KMT2AMEN1KCNH2CYP3A4
Water SCHEMBL10589317 0.97 TDP1 (0.93) TDP1KMT2AMEN1KCNH2CYP3A4
Hydrogen Sulfide SCHEMBL7866760 0.97 TDP1 (0.93) TDP1KMT2AMEN1KCNH2CYP3A4
SCHEMBL8745318 0.97 TDP1 (0.93) TDP1KMT2AMEN1KCNH2CYP3A4
Methane SCHEMBL1599658 0.97 TDP1 (0.93) TDP1KMT2AMEN1KCNH2CYP3A4
Water SCHEMBL3137651 0.97 TDP1 (0.93) TDP1KMT2AMEN1KCNH2CYP3A4
Hydrochloric Acid SCHEMBL874057 0.97 TDP1 (0.93) TDP1KMT2AMEN1KCNH2CYP3A4
Hydrochloric Acid SCHEMBL504482 0.97 TDP1 (0.93) TDP1KMT2AMEN1KCNH2CYP3A4
Hydrochloric Acid SCHEMBL94882 0.97 TDP1 (0.93) TDP1KMT2AMEN1KCNH2CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 17782 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12631634-B2 Histochemical and cytochemical methods for detecting NTRK fusion proteins VENTANA MEDICAL SYSTEMS, INC. (US) 2026-05-19 US claimed
US-12578340-B2 Determination of canine TK1 protein levels ALERTIX VETERINARY DIAGNOSTICS AB (SE) 2026-03-17 US claimed
EP-4211663-B1 A SCORING METHOD FOR AN ANTI-B7H4 ANTIBODY-DRUG CONJUGATE THERAPY MEDIMMUNE LTD (GB) 2026-02-18 EP claimed
EP-4692791-A1 METHOD FOR DETECTING CELL MEMBRANE PROTEIN TORAY INDUSTRIES, INC. (JP) 2026-02-11 EP claimed
US-20260016462-A1 HIGH PRECISION MICROPURIFICATION SYSTEM AND METHODS OF USE AVONEUX MEDICAL INST LLC (US) 2026-01-15 US claimed
EP-4677362-A1 ENZYME LINKED IMMUNOASSAY WITH DIFFUSION RATE LIMITING MEDIUM Elleon Biotech Limited (HK) 2026-01-14 EP claimed
EP-4211598-B1 A SCORING METHOD FOR AN ANTI-HER2 ANTIBODY-DRUG CONJUGATE THERAPY ASTRAZENECA UK LTD (GB) 2026-01-07 EP claimed
US-12509735-B2 Use of probes to detect toxinogenic cyanobacteria, detection method and corresponding kits MICROBIA ENVIRONNEMENT (FR) 2025-12-30 US claimed
EP-3853384-B1 USE OF PROBES TO DETECT TOXIC ALGAE, DETECTION METHOD AND CORRESPONDING KITS MICROBIA ENVIRONNEMENT (FR) 2025-11-26 EP claimed
US-20250352674-A1 COMPOSITIONS AND METHODS FOR MODULATING NEURONAL EXCITABILITY THE BROAD INSTITUTE, INC. (US) 2025-11-20 US claimed
US-4312976-A Single-stage melt polymerization process for the production of high molecular weight polybenzimidazole CELANESE CORPORATION (US) 1982-01-26 US claimed
EP-0041677-A2 Radiation reactive precursors of highly heat-resistant polymers, and their use SIEMENS AKTIENGESELLSCHAFT (DE) 1981-12-16 EP claimed
US-4238591-A BIS-MALEIMIDE, SILANEDIOL OR SILOXANE RHONE-POULENC INDUSTRIES (FR) 1980-12-09 US claimed
US-4201221-A Diagnostic test for allergic disorders and kit therefor ALI MAJID 1980-05-06 US claimed
US-4200508-A Method and composition for detecting antigenic substances HIRAI HIDEMATSU (JP) 1980-04-29 US claimed
US-4045414-A New di-substituted meta-terphenyl compounds and resulting polymers INSTITUT FRANCAIS DU PETROLE (FR) 1977-08-30 US claimed
US-4005058-A Process for the formation and recovery of poly(bisbenzimidazoenzophenanthroline) CELANESE CORPORATION (US) 1977-01-25 US claimed
US-3987015-A PROCESS FOR THE PRODUCTION OF PARTICULATE POLYMERIC MATERIAL HAVING AN UNUSUALLY HIGH SURFACE AREA CELANESE CORPORATION (US) 1976-10-19 US claimed
US-3969325-A Production of particulate BBB type polymer having an unusually high surface area CELANESE CORPORATION (US) 1976-07-13 US claimed
US-3943175-A Synthesis of pure 3,3'-diaminobenzidine CELANESE CORPORATION (US) 1976-03-09 US claimed