Phorone

Phorone

SCHEMBL23856063

CC(C)=CC(=O)C=C(C)C.CC(C)=CC(=O)C=C(C)C

nearest known ligand 0.39

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 3/20 0.39
ALDH1A1 P00352 4/20 0.38
TDP1 Q9NUW8 2/20 0.38
TSHR P16473 2/20 0.36
THPO P40225 1/20 0.36
FFAR3 O14843 1/20 0.36
LCK P06239 1/20 0.36
FYN P06241 1/20 0.36
TRPA1 O75762 1/20 0.35
CA1 P00915 2/20 0.33
ALOX15 P16050 1/20 0.33
BLM P54132 1/20 0.33
PMP22 Q01453 1/20 0.33
NPC1 O15118 2/20 0.31
RAB9A P51151 2/20 0.31
SMN1; SMN2 Q16637 2/20 0.31
NFKB1 P19838 1/20 0.31
NFKB2 Q00653 1/20 0.31
RELA Q04206 1/20 0.31
GAA P10253 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Phorone SCHEMBL157728 1.00 LMNA (0.39) LMNAALDH1A1TDP1TSHRTHPO
Phorone SCHEMBL28899536 0.96 LMNA (0.36) LMNAALDH1A1TDP1TSHRTHPO
Phorone SCHEMBL30396963 0.96 LMNA (0.36) LMNAALDH1A1TDP1TSHRTHPO
Phorone SCHEMBL27801489 0.96 LMNA (0.36) LMNAALDH1A1TDP1TSHRTHPO
Phorone SCHEMBL32672539 0.96 LMNA (0.36) LMNAALDH1A1TDP1TSHRTHPO
Phorone SCHEMBL5084762 0.96 LMNA (0.36) LMNAALDH1A1TDP1TSHRTHPO
Phorone SCHEMBL27547562 0.89 SMN1; SMN2 (0.32) LMNAALDH1A1TDP1TSHRTRPA1
SCHEMBL30666388 0.84
Phorone SCHEMBL22129179 0.84
Phorone SCHEMBL28117521 0.84

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4126763-A1 ZEOLITIC MATERIAL HAVING A FRAMEWORK STRUCTURE COMPRISING SI, O, AND TI BASF SE (DE) 2023-02-08 EP claimed
CN-115348950-A Zeolite material having a framework structure comprising Si, O and Ti 巴斯夫欧洲公司 2022-11-15 CN claimed
WO-2021191135-A1 ZEOLITIC MATERIAL HAVING A FRAMEWORK STRUCTURE COMPRISING SI, O, AND TI BASF SE (DE) 2021-09-30 WO claimed
US-20230191378-A1 ZEOLITIC MATERIAL HAVING A FRAMEWORK STRUCTURE COMPRISING SI, O, AND TI BASF SE (DE) 2023-06-22 US disclosed
EP-4126763-A1 ZEOLITIC MATERIAL HAVING A FRAMEWORK STRUCTURE COMPRISING SI, O, AND TI BASF SE (DE) 2023-02-08 EP disclosed
CN-115348950-A Zeolite material having a framework structure comprising Si, O and Ti 巴斯夫欧洲公司 2022-11-15 CN disclosed
WO-2021191135-A1 ZEOLITIC MATERIAL HAVING A FRAMEWORK STRUCTURE COMPRISING SI, O, AND TI BASF SE (DE) 2021-09-30 WO disclosed