Phorone

Phorone

SCHEMBL5084762

CC(C)=CC(=O)C=C(C)C.N.N

nearest known ligand 0.36

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.36
ALDH1A1 P00352 3/20 0.35
TDP1 Q9NUW8 1/20 0.35
TSHR P16473 2/20 0.33
TRPA1 O75762 1/20 0.33
THPO P40225 1/20 0.33
FFAR3 O14843 1/20 0.33
LCK P06239 1/20 0.33
FYN P06241 1/20 0.33
CA1 P00915 1/20 0.31
ALOX15 P16050 1/20 0.31
BLM P54132 1/20 0.31
PMP22 Q01453 1/20 0.31
NPC1 O15118 2/20 0.30
RAB9A P51151 2/20 0.30
SMN1; SMN2 Q16637 2/20 0.30
NFKB1 P19838 1/20 0.30
NFKB2 Q00653 1/20 0.30
RELA Q04206 1/20 0.30
GAA P10253 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Phorone SCHEMBL157728 0.96 LMNA (0.39) LMNAALDH1A1TDP1TSHRTRPA1
Phorone SCHEMBL23856063 0.96 LMNA (0.39) LMNAALDH1A1TDP1TSHRTRPA1
Phorone SCHEMBL30396963 0.92 LMNA (0.36) LMNAALDH1A1TDP1TSHRTRPA1
Phorone SCHEMBL28899536 0.92 LMNA (0.36) LMNAALDH1A1TDP1TSHRTRPA1
Phorone SCHEMBL32672539 0.92 LMNA (0.36) LMNAALDH1A1TDP1TSHRTRPA1
Phorone SCHEMBL27801489 0.92 LMNA (0.36) LMNAALDH1A1TDP1TSHRTRPA1
Phorone SCHEMBL27547562 0.86 SMN1; SMN2 (0.32) LMNAALDH1A1TDP1TSHRTRPA1
SCHEMBL30666388 0.81
Phorone SCHEMBL22129179 0.81
Phorone SCHEMBL28117521 0.81

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3668918-A1 PROCESS FOR THE MANUFACTURING OF A POLYMER WITH URETHANE GROUPS BASF SE (DE) 2020-06-24 EP disclosed
EP-3668917-A1 PROCESS FOR THE MANUFACTURING OF A POLYMER WITH URETHANE GROUPS BASF SE (DE) 2020-06-24 EP disclosed
WO-2019034473-A1 PROCESS FOR THE MANUFACTURING OF A POLYMER WITH URETHANE GROUPS BASF SE (DE) 2019-02-21 WO disclosed
WO-2019034470-A1 PROCESS FOR THE MANUFACTURING OF A POLYMER WITH URETHANE GROUPS BASF SE (DE) 2019-02-21 WO disclosed
US-20140039135-A1 CROSS-LINKED REACTIVE POLYMER MICROPARTICLES DIKIC TAMARA (NL) 2014-02-06 US disclosed
US-8212078-B2 Making chain extenders with slower cure rates; reacting a ketone and/or aldehyde with a primary amine in the presence of an acidic ion exchange resin and hydrogenation agent; making diimine same way but excluding hydrogenation agent; e.g. N,N'-di-5-nonyl-isophoronediamine ALBEMARLE CORPORATION (US) 2012-07-03 US disclosed
US-20080194788-A1 Diimines and Secondary Diamines ALBEMARLE CORPORATION (US) 2008-08-14 US disclosed
WO-2005095540-A1 PHOTOCHROMIC OPTICAL ARTICLE TRANSITIONS OPTICAL, INC. (US) 2005-10-13 WO disclosed
EP-1523506-A1 NEW DIFUNCTIONAL PHOTOINITIATORS Ciba SC Holding AG (CH) 2005-04-20 EP disclosed
WO-2004009651-A1 NEW DIFUNCTIONAL PHOTOINITIATORS CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 2004-01-29 WO disclosed
EP-0660950-A1 A PROCESS FOR PREPARING A BINDER RESIN USEFUL IN ELECTROPHOTOGRAPHIC TONER LUCKY, LTD. (KR) 1995-07-05 EP disclosed
EP-0581642-A1 Polymers and copolymers prepared by the addition of di-carboxy terminated oligomers to bisoxazines or bisoxazolines ELF ATOCHEM S.A. (FR) 1994-02-02 EP disclosed
EP-0346982-A1 Liquid coating composition curable at ambient temperatures AKZO N.V. (NL) 1989-12-20 EP disclosed
EP-0336391-A2 Reversibly color-changeable materials TEIJIN LIMITED (JP) 1989-10-11 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080194788-A1 Diimines and Secondary Diamines DDT, DDC, AOC1 LMNA 3427/4885ALDH1A1 252/4885TDP1 1248/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.