Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH1 | P35367 | 1/20 | 0.57 |
| ▸ | TGM2 | P21980 | 1/20 | 0.54 |
| ▸ | ITGB3 | P05106 | 7/20 | 0.50 |
| ▸ | ITGA2B | P08514 | 7/20 | 0.50 |
| ▸ | OPRK1 | P41145 | 3/20 | 0.49 |
| ▸ | CTSK | P43235 | 2/20 | 0.47 |
| ▸ | IDO1 | P14902 | 1/20 | 0.47 |
| ▸ | TDO2 | P48775 | 1/20 | 0.47 |
| ▸ | CCR1 | P32246 | 1/20 | 0.46 |
| ▸ | PPARG | P37231 | 1/20 | 0.46 |
| ▸ | PPARA | Q07869 | 1/20 | 0.46 |
| ▸ | DPP4 | P27487 | 1/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.46 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23856082 | 1.00 | HRH1 (0.57) | HRH1TGM2ITGB3ITGA2BOPRK1 | |
| SCHEMBL5967157 | 0.83 | HRH1 (0.59) | HRH1ITGB3ITGA2BOPRK1CTSK | |
| SCHEMBL15689075 | 0.82 | ITGB3 (0.63) | HRH1ITGB3ITGA2BOPRK1CTSK | |
| SCHEMBL19924796 | 0.81 | HRH1 (0.62) | HRH1ITGB3ITGA2BOPRK1CTSK | |
| SCHEMBL19924794 | 0.81 | HRH1 (0.62) | HRH1ITGB3ITGA2BOPRK1CTSK | |
| SCHEMBL23135998 | 0.81 | DPP4 (0.49) | TGM2OPRK1CTSKCCR1DPP4 | |
| SCHEMBL5651104 | 0.77 | KYNU (0.53) | HRH1OPRK1CTSK | |
| SCHEMBL7520315 | 0.76 | HRH1 (0.62) | HRH1ITGB3ITGA2BOPRK1PPARG | |
| SCHEMBL16435200 | 0.76 | HRH1 (0.52) | HRH1ITGB3ITGA2BOPRK1CTSK | |
| SCHEMBL27033000 | 0.76 | DPP4 (0.45) | TGM2OPRK1DPP4KCNH2DPP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021191827-A1 | TRIPEPTIDES DERIVATIVES FOR TREATING SARS-COV-2 INFECTIONS | GLAXOSMITHKLINE INTELLECTUAL PROPERTY DEVELOPMENT LIMITED (GB) | 2021-09-30 | — | — | WO | disclosed |