Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 2/20 | 0.51 |
| ▸ | TSHR | P16473 | 7/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.40 |
| ▸ | TP53 | P04637 | 3/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | AKR1B10 | O60218 | 4/20 | 0.36 |
| ▸ | AKR1B1 | P15121 | 4/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
| ▸ | AKT1 | P31749 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15405611 | 0.92 | THRB (0.49) | THRBTSHRALDH1A1TP53HIF1A | |
| SCHEMBL237894 | 0.85 | THRB (0.46) | THRBTSHRALDH1A1TP53HIF1A | |
| SCHEMBL234086 | 0.78 | POLB (0.41) | THRBTSHRALDH1A1CYP3A4HSD17B10 | |
| SCHEMBL7161569 | 0.78 | THRB (0.47) | THRBTSHRALDH1A1TP53HIF1A | |
| SCHEMBL4661261 | 0.77 | THRB (0.51) | THRBTSHRALDH1A1TP53HIF1A | |
| SCHEMBL28115369 | 0.77 | THRB (0.51) | THRBTSHRALDH1A1TP53HIF1A | |
| SCHEMBL17287246 | 0.76 | THRB (0.54) | THRBTSHRALDH1A1TP53HIF1A | |
| SCHEMBL29008219 | 0.76 | THRB (0.54) | THRBTSHRALDH1A1TP53HIF1A | |
| SCHEMBL6537025 | 0.75 | THRB (0.54) | THRBTSHRALDH1A1TP53HIF1A | |
| SCHEMBL15404814 | 0.75 | AKR1B10 (0.40) | ALDH1A1AKR1B10AKR1B1HCAR2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9745406-B2 | Curable composition | CEMEDINE CO., LTD. (JP) | 2017-08-29 | — | — | US | disclosed |
| EP-2412756-B1 | CURABLE COMPOSITION | CEMEDINE CO LTD (JP) | 2016-12-21 | — | — | EP | disclosed |
| EP-2412756-A1 | CURABLE COMPOSITION | CEMEDINE CO., LTD. (JP) | 2012-02-01 | — | — | EP | disclosed |
| US-20120004371-A1 | CURABLE COMPOSITION | CEMEDINE CO., LTD. (JP) | 2012-01-05 | — | — | US | disclosed |