Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A9 | P48067 | 2/20 | 0.35 |
| ▸ | PHGDH | O43175 | 5/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.31 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.31 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.31 |
| ▸ | CXCR3 | P49682 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19331263 | 0.83 | PHGDH (0.50) | SLC6A9PHGDHCYP2D6ALDH1A1 | |
| SCHEMBL25153797 | 0.75 | PHGDH (0.51) | SLC6A9PHGDH | |
| SCHEMBL26373069 | 0.75 | PHGDH (0.49) | SLC6A9PHGDHCYP2D6ALDH1A1MEN1 | |
| SCHEMBL19343383 | 0.73 | PHGDH (0.40) | SLC6A9PHGDH | |
| SCHEMBL19343573 | 0.73 | SLC6A9 (0.50) | SLC6A9CYP2D6ALDH1A1POLBMEN1 | |
| SCHEMBL23366353 | 0.72 | SLC6A9 (0.38) | SLC6A9PHGDH | |
| SCHEMBL19331274 | 0.72 | PHGDH (0.48) | SLC6A9PHGDHCYP2D6ALDH1A1MEN1 | |
| SCHEMBL19344079 | 0.71 | PHGDH (0.46) | SLC6A9PHGDHALDH1A1MEN1LMNA | |
| SCHEMBL23366366 | 0.70 | SMN1; SMN2 (0.42) | SLC6A9CYP2D6ALDH1A1POLBKMT2A | |
| SCHEMBL19343446 | 0.70 | PHGDH (0.59) | SLC6A9PHGDH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3884939-A1 | 3-PHOSPHOGLYCERATE DEHYDROGENASE INHIBITORS AND USES THEREOF | Raze Therapeutics, Inc. (US) | 2021-09-29 | — | — | EP | disclosed |