Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.62 |
| ▸ | MAPT | P10636 | 3/20 | 0.61 |
| ▸ | GLA | P06280 | 2/20 | 0.61 |
| ▸ | HPGD | P15428 | 2/20 | 0.61 |
| ▸ | ACHE | P22303 | 1/20 | 0.61 |
| ▸ | NQO2 | P16083 | 2/20 | 0.58 |
| ▸ | NPC1 | O15118 | 3/20 | 0.54 |
| ▸ | POLB | P06746 | 2/20 | 0.54 |
| ▸ | RAB9A | P51151 | 2/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
| ▸ | CASP1 | P29466 | 2/20 | 0.50 |
| ▸ | HTT | P42858 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.50 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | ATM | Q13315 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31242880 | 1.00 | ALDH1A1 (0.62) | ALDH1A1MAPTGLAHPGDACHE | |
| SCHEMBL29524245 | 1.00 | ALDH1A1 (0.62) | ALDH1A1MAPTGLAHPGDACHE | |
| Ammonia Solution, Strong SCHEMBL27985513 | 0.98 | ALDH1A1 (0.60) | ALDH1A1MAPTGLAHPGDACHE | |
| SCHEMBL13156498 | 0.96 | NQO2 (0.60) | ALDH1A1MAPTGLAHPGDACHE | |
| Pyridine SCHEMBL28887650 | 0.90 | ALDH1A1 (0.52) | ALDH1A1MAPTGLAHPGDACHE | |
| SCHEMBL19198262 | 0.87 | NQO2 (0.60) | ALDH1A1MAPTGLAHPGDACHE | |
| SCHEMBL9394410 | 0.87 | ALDH1A1 (0.62) | ALDH1A1MAPTGLAHPGDACHE | |
| Acridine SCHEMBL463236 | 0.86 | ALDH1A1 (0.77) | ALDH1A1MAPTGLAHPGDACHE | |
| SCHEMBL20272948 | 0.86 | ALDH1A1 (0.54) | ALDH1A1MAPTGLAHPGDACHE | |
| SCHEMBL29066655 | 0.84 | ALDH1A1 (0.58) | ALDH1A1MAPTGLAHPGDACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 102 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114685427-A | Quinoline bipyridyl compound and application thereof in organic electroluminescent element | 常州强力昱镭光电材料有限公司 | 2022-07-01 | — | — | CN | claimed |
| CN-104292227-B | A kind of aza-acridine aromatic rings derivant and preparation method and application | 河南中医学院 | 2016-09-28 | — | — | CN | claimed |
| CN-104292227-A | Aza-acridine aromatic ring derivative as well as preparation method and application thereof | UNIV HENAN TCM | 2015-01-21 | — | — | CN | claimed |
| EP-1140932-B1 | 1,8-BENZONAPHTHYRIDINE DERIVATIVES | AVENTIS PHARMA SA (FR) | 2004-03-17 | — | — | EP | claimed |
| EP-1140932-A1 | 1,8-BENZONAPHTHYRIDINE DERIVATIVES | Aventis Pharma S.A. (FR) | 2001-10-10 | — | — | EP | claimed |
| WO-2000037467-A1 | 1,8-BENZONAPHTHYRIDINE DERIVATIVES | AVENTIS PHARMA S.A. (FR) | 2000-06-29 | — | — | WO | claimed |
| EP-0641341-B1 | METHOD FOR PREPARING BENZO [b]NAPHTHYRIDINES | RHONE POULENC RORER SA (FR) | 2000-03-01 | — | — | EP | claimed |
| EP-0606382-B1 | 1,8-BENZONAPHTHYRIDINE DERIVATIVES AND ANTIMICROBIAL COMPOSITIONS | BELLON LABOR SA ROGER (FR) | 1998-05-13 | — | — | EP | claimed |
| US-5624933-A | Process for the preparation of a 6-fluoro-2-halo-quinoline | RHONE-POULENC RORER S.A. (FR) | 1997-04-29 | — | — | US | claimed |
| US-5484921-A | Process for preparing benzo[b]naphthyridines | LABORATOIRE ROGER BELLON (FR) | 1996-01-16 | — | — | US | claimed |
| EP-0606382-A1 | 1,8-BENZONAPHTHYRIDINE DERIVATIVES AND ANTIMICROBIAL COMPOSITIONS | LABORATOIRE ROGER BELLON (FR) | 1994-07-20 | — | — | EP | claimed |
| EP-0431991-B1 | 1,8-Benzonaphthyridine derivatives, their preparation and compositions containing them | BELLON LABOR SA ROGER (FR) | 1994-01-12 | — | — | EP | claimed |
| EP-0379412-B1 | 1,8-Benzonaphthyridine derivatives, their preparation and compositions containing them | BELLON LABOR SA ROGER (FR) | 1993-12-01 | — | — | EP | claimed |
| WO-1993007144-A1 | 1,8-BENZONAPHTHYRIDINE DERIVATIVES AND ANTIMICROBIAL COMPOSITIONS | LABORATOIRE ROGER BELLON (FR) | 1993-04-15 | — | — | WO | claimed |
| WO-1993007145-A1 | METHOD FOR PREPARING BENZO[b]NAPHTHYRIDINES | LABORATOIRE ROGER BELLON (FR) | 1993-04-15 | — | — | WO | claimed |
| EP-0536035-A1 | 1,8-Benzonaphthyridine derivatives and antimicrobial compositions | LABORATOIRE ROGER BELLON (FR) | 1993-04-07 | — | — | EP | claimed |
| EP-0431991-A1 | 1,8-Benzonaphthyridine derivatives, their preparation and compositions containing them | Société anonyme dite: LABORATOIRE ROGER BELLON (FR) | 1991-06-12 | — | — | EP | claimed |
| EP-0379412-A1 | 1,8-Benzonaphthyridine derivatives, their preparation and compositions containing them | Société anonyme dite: LABORATOIRE ROGER BELLON (FR) | 1990-07-25 | — | — | EP | claimed |
| US-4061638-A | Organocalciumpyridine-type polymerization initiators | PHILLIPS PETROLEUM COMPANY (US) | 1977-12-06 | — | — | US | claimed |
| US-3997708-A | ADDITION | PHILLIPS PETROLEUM COMPANY (US) | 1976-12-14 | — | — | US | claimed |