Acridine

Acridine

SCHEMBL463236

c1ccc2nc3ccccc3cc2c1.c1ccc2ncccc2c1

nearest known ligand 0.77

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.77
MAPT P10636 3/20 0.68
GLA P06280 1/20 0.68
HPGD P15428 1/20 0.68
ACHE P22303 1/20 0.68
NPC1 O15118 2/20 0.59
POLB P06746 2/20 0.59
RAB9A P51151 1/20 0.59
CASP1 P29466 2/20 0.55
HTT P42858 2/20 0.55
KDM4E B2RXH2 1/20 0.55
TP53 P04637 1/20 0.55
HSP90AA1 P07900 1/20 0.55
HSP90AB1 P08238 1/20 0.55
TSHR P16473 1/20 0.55
ATM Q13315 1/20 0.55
SMN1; SMN2 Q16637 1/20 0.55
HSD17B10 Q99714 1/20 0.55
CYP1A2 P05177 2/20 0.50
MEN1 O00255 2/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Anthracene SCHEMBL5466102 0.91 ALDH1A1 (0.85) ALDH1A1MAPTGLAHPGDACHE
Quinoline SCHEMBL137291 0.91 ALDH1A1 (0.94) ALDH1A1MAPTGLAHPGDACHE
Quinoline SCHEMBL27594824 0.88 ALDH1A1 (0.90) ALDH1A1MAPTGLAHPGDACHE
Quinoline SCHEMBL27611581 0.88 ALDH1A1 (0.90) ALDH1A1MAPTGLAHPGDACHE
Phenazine SCHEMBL12804247 0.88 ALDH1A1 (0.90) ALDH1A1MAPTGLAHPGDACHE
Quinoline SCHEMBL29822171 0.88 ALDH1A1 (1.00) ALDH1A1MAPTGLAHPGDACHE
Quinoline SCHEMBL29349552 0.88 ALDH1A1 (1.00) ALDH1A1MAPTGLAHPGDACHE
Quinoline SCHEMBL32661377 0.88 ALDH1A1 (1.00) ALDH1A1MAPTGLAHPGDACHE
Quinoline SCHEMBL2774 0.88 ALDH1A1 (1.00) ALDH1A1MAPTGLAHPGDACHE
Quinoline SCHEMBL1270969 0.88 ALDH1A1 (1.00) ALDH1A1MAPTGLAHPGDACHE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 56 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11895915-B2 Organic light emitting diode and organic light emitting device having the same LG DISPLAY CO., LTD (KR) 2024-02-06 US claimed
CN-117362294-A Polyquinoline acridine diketone macrocyclic derivative and preparation method and application thereof 广东工业大学 2024-01-09 CN claimed
CN-1247051-C Organic electroluminescent device and producing method thereof UNIV TSINGHUA (CN) 2006-03-22 CN claimed
CN-1436028-A Organic electroluminescent device and producing method thereof UNIV TSINGHUA (CN) 2003-08-13 CN claimed
JP-3172522-B2 2001-06-04 JP claimed
WO-1989006231-A1 ASSAYS UTILIZING IMPROVED CHEMILUMINESCENT ESTERS, THIOESTERS AND AMIDES LONDON DIAGNOSTICS, INC. (US) 1989-07-13 WO claimed
CN-117362294-A Polyquinoline acridine diketone macrocyclic derivative and preparation method and application thereof 广东工业大学 2024-01-09 CN disclosed
CN-117362294-A Polyquinoline acridine diketone macrocyclic derivative and preparation method and application thereof 广东工业大学 2024-01-09 CN disclosed
CN-112447921-B Organic light emitting diode and organic light emitting device having the same 乐金显示有限公司 2024-01-02 CN disclosed
CN-112442015-B Organic compound having improved light emitting characteristics, organic light emitting diode and organic light emitting device containing the same 乐金显示有限公司 2023-10-24 CN disclosed
CN-111018837-B Organic compound, OLED having the same, and organic light emitting device 乐金显示有限公司 2023-04-28 CN disclosed
CN-111326666-B Organic light emitting diode and organic light emitting device having the same 乐金显示有限公司 2023-04-18 CN disclosed
CN-111349079-B Organic compound, OLED having the same, and organic light emitting device having the same 乐金显示有限公司 2023-04-18 CN disclosed
CN-1436028-A Organic electroluminescent device and producing method thereof UNIV TSINGHUA (CN) 2003-08-13 CN disclosed
CN-1398934-A Paint composition for metal product DAIHO PAINT CO LTD (JP) 2003-02-26 CN disclosed
CN-1396465-A Optical film ASAHI GLASS CO LTD (JP) 2003-02-12 CN disclosed
CN-1308327-A Record medium, record device and record method TOSHIBA KK (JP) 2001-08-15 CN disclosed
WO-2000071494-A1 PROCESS FOR ENHANCING THE VALUE OF HYDROCARBONACEOUS NATURAL RESOURCES JAMES W. BUNGER AND ASSOCIATES, INC. (US) 2000-11-30 WO disclosed
CN-1247188-A Novel polyamino acid derivative AJINOMOTO KK (JP) 2000-03-15 CN disclosed
EP-0062561-B1 DOSIMETER FOR THE MEASUREMENT OF ALPHA, GAMMA, X RAYS AND FAST NEUTRON DOSES, ESPECIALLY FOR LARGE DOSES MEASUREMENT Commissariat à l'Energie Atomique (FR) 1985-02-06 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11895915-B2 Organic light emitting diode and organic light emitting device having the same MAP1LC3A, MAP1LC3C, MAP1LC3B ALDH1A1 895/4885MAPT 89/4885GLA 2393/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.