Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRR1 | P24046 | 2/20 | 0.38 |
| ▸ | PAOX | Q6QHF9 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25610796 | 0.79 | CES1 (0.38) | ALDH1A1TDP1 | |
| SCHEMBL12196723 | 0.78 | — | — | |
| SCHEMBL5323535 | 0.76 | — | — | |
| SCHEMBL23056594 | 0.76 | — | — | |
| SCHEMBL16171991 | 0.76 | CA1 (0.43) | ALDH1A1TDP1 | |
| SCHEMBL8234927 | 0.75 | GRIK1 (0.52) | — | |
| SCHEMBL13880377 | 0.73 | TDP1 (0.45) | ALDH1A1TDP1 | |
| SCHEMBL17108806 | 0.72 | DPP4 (0.36) | GABRR1 | |
| SCHEMBL29191684 | 0.71 | ALDH1A1 (0.42) | ALDH1A1TDP1 | |
| SCHEMBL28851717 | 0.71 | CA1 (0.48) | GABRR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3885339-A1 | PROCESS FOR THE PREPARATION OF (R)-4-(1-(6-(4-(TRIFLUOROMETHYL)BENZYL)-6-AZASPIRO[2.5]OCTANE-5-CARBOXAMIDO)-CYCLOPROPYL) BENZOIC ACID OR A SALT THEREOF | Rottapharm Biotech S.r.l. (IT) | 2021-09-29 | — | — | EP | disclosed |