Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES1 | P23141 | 2/20 | 0.38 |
| ▸ | CES2 | O00748 | 1/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 4/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 4/20 | 0.36 |
| ▸ | HDAC8 | Q9BY41 | 4/20 | 0.36 |
| ▸ | FFAR3 | O14843 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 2/20 | 0.31 |
| ▸ | CTSD | P07339 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22305556 | 0.84 | CYP1A2 (0.38) | CES1CES2HDAC3HDAC1HDAC2 | |
| SCHEMBL11604570 | 0.83 | CES2 (0.39) | CES1CES2HDAC3HDAC1HDAC2 | |
| SCHEMBL15316792 | 0.81 | CES2 (0.38) | CES1CES2HDAC3HDAC1HDAC2 | |
| SCHEMBL27970840 | 0.81 | CYP1A2 (0.44) | CES1CES2HDAC3HDAC1HDAC2 | |
| SCHEMBL13880377 | 0.80 | TDP1 (0.45) | FFAR3ALDH1A1TDP1 | |
| SCHEMBL23864591 | 0.79 | GABRR1 (0.38) | ALDH1A1TDP1 | |
| SCHEMBL16171991 | 0.77 | CA1 (0.43) | ALDH1A1TDP1CA1CYP1A2 | |
| SCHEMBL6754080 | 0.77 | CES2 (0.40) | CES1CES2HDAC3HDAC1HDAC2 | |
| SCHEMBL104701 | 0.77 | — | — | |
| SCHEMBL2050674 | 0.77 | CES2 (0.43) | CES1CES2HDAC3HDAC1HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230294386-A9 | BARRIER LAYERS | BRUGG ROHR AG HOLDING (CH) | 2023-09-21 | — | — | US | disclosed |
| US-20230184368-A1 | THERMALLY INSULATED MEDIUM PIPES HAVING HFO-CONTAINING CELL GAS | BRUGG ROHR AG HOLDING (CH) | 2023-06-15 | — | — | US | disclosed |