Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 5/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | IDO1 | P14902 | 1/20 | 0.32 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.31 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23864208 | 0.90 | HPGD (0.32) | HPGDKDM4EALDH1A1HSD17B10IDO1 | |
| SCHEMBL23864738 | 0.85 | HPGD (0.34) | HPGDKDM4EALDH1A1HSD17B10ALOX12 | |
| SCHEMBL23864257 | 0.79 | CYP2C9 (0.35) | HPGDKDM4EALDH1A1GAAALOX12 | |
| SCHEMBL23864210 | 0.79 | HPGD (0.35) | HPGDKDM4EALDH1A1GAAHTT | |
| SCHEMBL23864239 | 0.78 | — | — | |
| SCHEMBL23864482 | 0.78 | TSHR (0.36) | HPGDALDH1A1PDCD1CD274MEN1 | |
| SCHEMBL23864375 | 0.76 | HDAC2 (0.37) | NR1H4HPGDKDM4EALDH1A1HSD17B10 | |
| SCHEMBL23864743 | 0.76 | HTT (0.32) | HPGDKDM4EALDH1A1HSD17B10CD274 | |
| SCHEMBL23864469 | 0.76 | HPGD (0.34) | HPGDKDM4EALDH1A1ALOX12HTT | |
| SCHEMBL23864573 | 0.76 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2968330-B1 | COMPOUNDS AND METHODS FOR INDUCING CHONDROGENESIS | SCRIPPS RESEARCH INST (US) | 2021-09-29 | — | — | EP | disclosed |